| Hemodynamic performance study on small diameter helical grafts. | |
| | |
MedLine Citation:
|
PMID: 19318918 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The use of helix geometry for arterial grafts has been proposed on the hypothesis that by intentionally inducing swirling or spiral flow in the grafts, hemodynamic performance of the grafts might be improved. To investigate their hemodynamic performance, the present study numerically simulated the flows in the helical grafts, not only for comparison with conventional grafts but for their parameter analysis of Dean Number, helical pitch, and amplitude. Results showed that the helical graft achieved three dimensionality swirling flow, more uniformly distributed flow field and high wall shear stress (WSS) which continued in the straight part of the graft downstream. However, increased pressure drop was predicted in helical graft; flow areas with low velocity will concentrate in one corner, which might possibly suffer from flow stagnation and inhabitation, leading to a possible vulnerability to hemodynamic failure, intimal hyperplasia (IH) and thrombosis. The parameter study indicates that even at the same Dean number but with different geometry, the hemodynamic performance of two grafts are totally different. Shorter helical pitch and larger helical amplitude do improve the graft's hemodynamic performance, but may not be mechanically robust or applicable clinically. The current study increases fundamental understanding of the flow mechanism in swirling flow grafts. |
| | |
Authors:
|
Tinghui Zheng; Yubo Fan; Yan Xiong; Wentao Jiang; Xiaoyan Deng |
Related Documents
:
|
8787698 - Sensitive and specific quantification of sirolimus (rapamycin) and its metabolites in b... 16904678 - Importance of flow division on transition to turbulence within an arteriovenous graft. 1296578 - A triangular cutting arteriotomy scissors facilitating end-to-side anastomoses. 7877228 - The anastomosis angle does change the flow fields at vascular end-to-side anastomoses i... 3604678 - Flow loaded canine carotid artery. ii. ultrastructural changes in the subendothelial la... 2650918 - Digital angiographic impulse response analysis of regional myocardial perfusion: linear... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: ASAIO journal (American Society for Artificial Internal Organs : 1992) Volume: 55 ISSN: 1538-943X ISO Abbreviation: ASAIO J. Publication Date: 2009 May-Jun |
Date Detail:
|
Created Date: 2009-05-11 Completed Date: 2009-07-16 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9204109 Medline TA: ASAIO J Country: United States |
Other Details:
|
Languages: eng Pagination: 192-9 Citation Subset: IM |
Affiliation:
|
Department of Applied Mechanics, Sichuan University, Chengdu, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Arteries
/
transplantation* Hemodynamics / physiology* Hemorheology / physiology Models, Cardiovascular* Shear Strength / physiology Stress, Mechanical Transplants* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Primary and secondary T-cell lymphomas of the breast: clinico-pathologic features of 11 cases.
Next Document: The administration of ciprofloxacin during continuous renal replacement therapy: pilot study.