Document Detail

Hemodynamic performance and incidence of patient-prosthesis mismatch of the complete supraannular perimount magna bioprosthesis in the aortic position.
MedLine Citation:
PMID:  16037868     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Complete supraannular placement and smaller stent design allow the implantation of a Perimount Magna bioprosthesis with a larger inner diameter than that of a standard Perimount. This study compares the hemodynamic performance and the incidence of patient-prosthesis mismatch (PPM) of both prostheses. METHODS: 128 patients underwent aortic valve replacement, receiving either a Magna (n = 57) or a standard (n = 71) prosthesis. Inner aortic annulus diameter was measured intraoperatively by a hegar dilator to match echocardiographically obtained results to the annulus diameter instead of matching them to labelled valve size. RESULTS: The Magna was significantly superior with respect to mean pressure gradient and effective orifice area in patients with an annulus diameter of 22-23 mm. In patients with an annulus diameter < 22 mm or > 23 mm, there was a non-significant trend towards superior hemodynamics in the Magna group. Severe PPM (effective orifice area index < or = 0.65 cm (2)/m (2)) was present in 11.1% (Magna) vs. 42.1% (Standard) of patients with an annulus diameter < 22 mm; in 0% (Magna) vs. 13.8% (Standard) with an annulus diameter of 22-23 mm; no PPM was seen in patients with annulus diameter > 23 mm in both groups. CONCLUSIONS: The Perimount Magna had a significantly reduced incidence of patient-prosthesis mismatch and superior hemodynamics compared to the standard Perimount.
F Botzenhardt; W B Eichinger; R Guenzinger; S Bleiziffer; I Wagner; R Bauernschmitt; R Lange
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Thoracic and cardiovascular surgeon     Volume:  53     ISSN:  0171-6425     ISO Abbreviation:  Thorac Cardiovasc Surg     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-07-22     Completed Date:  2005-12-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7903387     Medline TA:  Thorac Cardiovasc Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  226-30     Citation Subset:  IM    
German Heart Center Munich, Department of Cardiovascular Surgery, Munich, Germany.
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MeSH Terms
Age Factors
Aged, 80 and over
Aortic Valve Insufficiency / diagnosis,  mortality,  surgery*
Aortic Valve Stenosis / diagnosis,  mortality,  surgery*
Follow-Up Studies
Heart Valve Prosthesis*
Heart Valve Prosthesis Implantation / adverse effects,  methods*
Hemodynamics / physiology*
Middle Aged
Postoperative Complications / mortality
Prospective Studies
Prosthesis Design
Prosthesis Failure
Risk Assessment
Severity of Illness Index
Sex Factors
Statistics, Nonparametric
Survival Rate
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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