Document Detail

Hemodynamic patterns of meningococcal shock in children.
MedLine Citation:
PMID:  3338278     Owner:  NLM     Status:  MEDLINE    
Meningococcal shock still is associated with high mortality. Along with antibiotics and control of metabolic derangements, standard therapy involves monitoring and maintaining numerous cardiorespiratory variables. From 1980 to 1985, 39 children with meningococcal shock were treated in our pediatric ICU. We obtained full hemodynamic monitoring in 18 (12 survivors, six nonsurvivors). Two hemodynamic patterns were observed: hypovolemia and cardiac failure. Early death was generally related to refractory hypovolemia, probably secondary to severe capillary leak. Survival usually occurred when noticeable cardiac failure was controlled with early use of catecholamines and judicious fluid management. Because cardiac failure only slowly recovered, a therapeutic approach that aims not at normal variables but, rather, at survival variables seems appropriate.
J C Mercier; F Beaufils; J F Hartmann; D Azéma
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  16     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1988 Jan 
Date Detail:
Created Date:  1988-02-29     Completed Date:  1988-02-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  27-33     Citation Subset:  AIM; IM    
Service de Réanimation Pédiatrique, Hôpital Bretonneau, Paris, France.
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MeSH Terms
Blood Volume
Cardiac Output
Child, Preschool
Heart Failure / etiology
Heart Rate
Intensive Care Units
Meningococcal Infections / mortality,  physiopathology*,  therapy
Pulmonary Wedge Pressure
Shock, Septic / mortality,  physiopathology*,  therapy

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