Document Detail


Hemodynamic patterns of blunt and penetrating injuries.
MedLine Citation:
PMID:  17116559     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The aims of this prospective observational study were to describe early hemodynamic patterns of blunt and penetrating truncal injury and to evaluate outcomes prediction using noninvasive hemodynamic monitoring with a mathematical model tested against actual in-hospital outcomes. The hypothesis was that traumatic shock is a circulatory disorder that can be monitored by noninvasive hemodynamic parameters that reflect cardiac, pulmonary, and tissue perfusion functions. STUDY DESIGN: The cardiac index (CI), heart rate (HR), mean arterial pressure (MAP), pulse oximetry (SapO(2)), transcutaneous oxygen tension indexed to FiO(2) (PtcO(2)/FiO(2)), and carbon dioxide (PtcCO(2)) tensions were monitored beginning shortly after emergency department admission in 657 emergency patients with severe blunt and penetrating chest, abdominal, and extremity trauma. Of these, 113 patients had associated head injury, and these patients also were analyzed separately. A search and display mathematical model, with a decision support program, was based on continuous online, real-time, noninvasive hemodynamic monitoring. RESULTS: There were similar patterns in the blunt and penetrating injuries; the cardiac index, mean arterial pressure, pulse oximetry, transcutaneous oxygen tension indexed to FiO(2), and survival probability values of the survivors were significantly higher (p < 0.01) than the corresponding values of those who died, although heart rate and carbon dioxide tension were higher in the nonsurvivors during the first 24 hours after their emergency department admission. These patterns occurred more rapidly in patients with penetrating injuries. After initial resuscitation in the emergency department, results were correlated with actual outcomes at hospital discharge and found to be 88% correct. CONCLUSIONS: Early noninvasive hemodynamic monitoring with a computerized information system provided a feasible pattern recognition program for outcomes prediction and therapeutic decision support.
Authors:
Kevin Jun-Qiang Lu; Li-Chien Chien; Charles C J Wo; Demetrios Demetriades; William C Shoemaker
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2006-10-02
Journal Detail:
Title:  Journal of the American College of Surgeons     Volume:  203     ISSN:  1072-7515     ISO Abbreviation:  J. Am. Coll. Surg.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-22     Completed Date:  2007-02-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9431305     Medline TA:  J Am Coll Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  899-907     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, LAC+USC Medical Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Gas Monitoring, Transcutaneous
Blood Pressure
Cardiac Output
Cardiovascular Physiological Phenomena*
Electric Impedance
Female
Heart Rate
Humans
Male
Models, Statistical
Monitoring, Physiologic*
Oximetry
ROC Curve
Shock, Traumatic / physiopathology
Survival Analysis
Wounds, Nonpenetrating / mortality,  physiopathology*
Wounds, Penetrating / mortality,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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