Document Detail


Hemodynamic measurements in human arterial casts, and their correlation with histology and luminal area.
MedLine Citation:
PMID:  19530808     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A new approach is presented for studying the vascular response to hemodynamic stress. A laser doppler anemometer is used to make velocity measurements very near the walls of human arterial casts; these measurements are then correlated with the histology of the artery from which the cast was made. Several illustrative results are given which suggest that the velocity profiles along the outer walls of aortic bifurcations may be significantly determined by the longitudinal variation of cross-sectional area. The shapes of these profiles were qualitatively different for each cast studied. In one specimen, the location of initial lipid deposits appeared to correlate with flow acceleration.
Authors:
M H Friedman; C B Bargeron; G M Hutchins; F F Mark; O J Deters
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of biomechanical engineering     Volume:  102     ISSN:  1528-8951     ISO Abbreviation:  J Biomech Eng     Publication Date:  1980 Aug 
Date Detail:
Created Date:  2009-06-17     Completed Date:  2009-12-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909584     Medline TA:  J Biomech Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  247     Citation Subset:  IM    
Affiliation:
The Johns Hopkins University, Applied Physics Laboratory, Laurel, MD. 20810, USA.
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MeSH Terms
Descriptor/Qualifier:
Anatomy, Cross-Sectional / methods*
Arteries / physiology*
Blood Flow Velocity / physiology*
Blood Pressure / physiology*
Casts, Surgical*
Computer Simulation
Humans
Models, Anatomic*
Models, Cardiovascular*
Grant Support
ID/Acronym/Agency:
HL 21270/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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