Document Detail

Hemodynamic management in pulmonary embolism and acute hypoxemic respiratory failure.
MedLine Citation:
PMID:  2403515     Owner:  NLM     Status:  MEDLINE    
Management of patients with the adult respiratory distress syndrome should be directed toward maintaining adequate cardiac output and tissue oxygenation without exacerbating pulmonary edema. The aim of therapy should be to maintain low left ventricular filling pressure, which will tend to decrease the rate of edema formation. If cardiac output is low or decreases as a function of therapy, flow may be increased with inotropic agents. When a marked decline in cardiac output complicates pulmonary embolism, norepinephrine may be an excellent drug for at least short-term maintenance of hemodynamic stability. When a moderate decrease in cardiac output complicates an increase in right ventricular afterload, isoproterenol or dobutamine may be used to increase flow. Rapid administration of recombinant tissue plasminogen activator may be the treatment of choice of pulmonary thromboembolism associated with a low output state.
R M Prewitt
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Critical care medicine     Volume:  18     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1990 Jan 
Date Detail:
Created Date:  1990-02-06     Completed Date:  1990-02-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S61-9     Citation Subset:  AIM; IM    
Section of Cardiology, University of Manitoba, Winnipeg, Canada.
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MeSH Terms
Acute Disease
Anoxia / physiopathology*,  therapy
Cardiac Output / drug effects
Cardiac Output, Low / physiopathology
Cardiotonic Agents / therapeutic use
Combined Modality Therapy
Fibrinolytic Agents / therapeutic use
Pulmonary Embolism / physiopathology*,  therapy
Respiratory Distress Syndrome, Adult / therapy
Vascular Resistance / drug effects
Reg. No./Substance:
0/Cardiotonic Agents; 0/Fibrinolytic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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