Document Detail

Hemodynamic instability after receiving intravenous Perflutren for contrast echocardiography in an elderly female.
MedLine Citation:
PMID:  15488089     Owner:  NLM     Status:  MEDLINE    
Myocardial contrast echocardiography (MCE) has been used with increasing frequency and is considered a safe way to improve left ventricular border opacification. Studies have consistently documented that MCE can improve the ability to assess both global and regional left ventricular function by echocardiography. We report the case of an 83-year-old female who developed immediate and sustained hemodynamic instability after the injection of Perflutren for a contrast echocardiogram. We reviewed the literature and found no such previous reactions with Perflutren. Based on the temporal sequence of hypotension following Perflutren injection along with other clinical data, we concluded that our patient's hemodynamic instability was most likely secondary to an anaphylactic reaction.
Ilya Blokh; Amanda Ganem; Elias P Bonaros; Bibiana D Stephen; Bart Steinberg; Stacey E Rosen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Echocardiography (Mount Kisco, N.Y.)     Volume:  21     ISSN:  0742-2822     ISO Abbreviation:  Echocardiography     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-10-18     Completed Date:  2006-08-18     Revised Date:  2008-05-30    
Medline Journal Info:
Nlm Unique ID:  8511187     Medline TA:  Echocardiography     Country:  United States    
Other Details:
Languages:  eng     Pagination:  613-5     Citation Subset:  IM    
Department of Internal Medicine, Long Island Jewish Hospital, New Hyde Park, New York 11040, USA.
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MeSH Terms
Aged, 80 and over
Anaphylaxis / chemically induced
Contrast Media / administration & dosage,  adverse effects*
Endocarditis, Bacterial / diagnosis,  microbiology
Fluorocarbons / administration & dosage,  adverse effects*
Hemodynamics / drug effects*
Infusions, Intravenous
Staphylococcal Infections / diagnosis,  microbiology
Reg. No./Substance:
0/Contrast Media; 0/Fluorocarbons; 76-19-7/perflutren

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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