Document Detail

Hemodynamic effects of positive end-expiratory pressure. Historical perspective.
MedLine Citation:
PMID:  3526888     Owner:  NLM     Status:  MEDLINE    
Mechanical ventilation with positive end-expiratory pressure has been known to increase arterial oxygen content for approximately 40 years. Early experiments demonstrated a diminution of cardiac output with the application of positive end-expiratory pressure, and it was not favored as a therapeutic modality until the 1960s, when it was found to be effective in the treatment of adult respiratory distress syndrome. In recent years, physiologists have methodically scrutinized the effects of positive end-expiratory pressure on each of the major determinants of cardiac output. Review of the progression of thought on this subject reinforces for today's clinician basic principles of cardiac performance and heart-lung interaction.
C J Van Hook; A D Carilli; E F Haponik
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of medicine     Volume:  81     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  1986 Aug 
Date Detail:
Created Date:  1986-09-25     Completed Date:  1986-09-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  307-10     Citation Subset:  AIM; IM    
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MeSH Terms
Cardiac Output
Positive-Pressure Respiration*
Respiratory Distress Syndrome, Adult / therapy

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