Document Detail

Hemodynamic effects of continuous positive-pressure ventilation and high-frequency jet ventilation with positive end-expiratory pressure in normal dogs.
MedLine Citation:
PMID:  6380937     Owner:  NLM     Status:  MEDLINE    
The hemodynamic effects of high-frequency jet ventilation (HFJV) at 60, 120, 240, and 480 breath/min, and conventional ventilation at 15 breath/min were compared in 6 anesthetized, paralyzed dogs, at 0, 10, and 20 cm H2O of positive end-expiratory pressure (PEEP). On HFJV at the same inspired oxygen, PaCO2, and PEEP levels, hemodynamic function improved significantly. Cardiac output was higher, whereas transmural CVP and pulmonary vascular resistances were lower. The improvement was primarily related to a decrease in mean airway pressure, particularly at higher PEEP levels. When PEEP was applied, hemodynamic function improved even when mean airway pressure was maintained constant. The findings suggest that lung volume was smaller during HFJV, and/or that lung volume changes during each respiratory cycle contributed to differences in venous return and ventricular function.
M Chiaranda; A Rubini; G Fiore; G Giron; G C Carlon
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  12     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1984-10-25     Completed Date:  1984-10-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  750-4     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure
Cardiac Output
Central Venous Pressure
Heart Rate
Lung / physiology
Lung Volume Measurements
Monitoring, Physiologic
Positive-Pressure Respiration*
Pulmonary Wedge Pressure
Respiration, Artificial / methods*
Vascular Resistance

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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