| Hemodynamic effects of ICI 118.587 (Corwin) in patients with mild cardiac failure after myocardial infarction. | |
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MedLine Citation:
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PMID: 2580158 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to compare the effects of intravenous ICI 118.587 (Corwin), a new cardioselective partial beta-agonist, and placebo given q. 12 h for 4 consecutive days, with invasive and noninvasive methods. Twelve patients with mild to moderate cardiac failure after a myocardial infarction were studied. We could not show any significant effect of Corwin on hemodynamics, systolic time intervals, heart rates, or blood pressures. We conclude that Corwin does not affect left ventricular function, as measured by hemodynamics and systolic time intervals, in the immediate postinfarction period in patients with mild to moderate heart failure. |
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Authors:
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G Svensson; N Rehnqvist; A Sjögren; L Erhardt |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of cardiovascular pharmacology Volume: 7 ISSN: 0160-2446 ISO Abbreviation: J. Cardiovasc. Pharmacol. Publication Date: 1985 Jan-Feb |
Date Detail:
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Created Date: 1985-05-16 Completed Date: 1985-05-16 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7902492 Medline TA: J Cardiovasc Pharmacol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 97-101 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Agonists
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pharmacology* Aged Female Heart Failure / etiology, physiopathology* Hemodynamics / drug effects* Humans Male Middle Aged Myocardial Contraction / drug effects Myocardial Infarction / complications, physiopathology* Propanolamines / pharmacology* Xamoterol |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Agonists; 0/Propanolamines; 81801-12-9/Xamoterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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