Document Detail

Hemodynamic effect of laser therapy in spontaneously hypertensive rats.
MedLine Citation:
PMID:  25211315     Owner:  NLM     Status:  In-Data-Review    
Systemic arterial hypertension (SAH) is considered to be the greatest risk factor for the development of neuro-cardiovascular pathologies, thus constituting a severe Public Health issue in the world. The Low-Level Laser Therapy (LLLT), or laser therapy, activates components of the cellular structure, therefore converting luminous energy into photochemical energy and leading to biophysical and biochemical reactions in the mitochondrial respiratory chain. The LLLT promotes cellular and tissue photobiomodulation by means of changes in metabolism, leading to molecular, cellular and systemic changes. The objective of this study was to analyze the action of low-level laser in the hemodynamic modulation of spontaneously hypertensive rats, in the long term. Animals (n = 16) were randomly divided into the Laser Group (n = 8), which received three weekly LLLT irradiations for seven weeks, and into the Sham Group (n = 8), which received three weekly simulations of laser for seven weeks, accounting for 21 applications in each group. After seven weeks, animals were cannulated by the implantation of a catheter in the left carotid artery. On the following day, the systemic arterial pressure was recorded. The Laser Group showed reduced levels of mean blood pressure, with statistically significant reduction (169 ± 4 mmHg* vs. 182 ± 4 mmHg from the Sham Group) and reduced levels of diastolic pressure (143 ± 4 mmHg* vs. 157 ± 3 mmHg from the Sham Group), revealing a 13 and 14 mmHg decrease, respectively. Besides, there was a concomitant important decline in heart rate (312 ± 14 bpm vs. 361 ± 13 bpm from the Sham Group). Therefore, laser therapy was able to produce hemodynamic changes, thus reducing pressure levels in spontaneously hypertensive rats.
Suely Tomimura; Bianca Passos Assumpção Silva; Iris Callado Sanches; Marina Canal; Fernanda Consolim-Colombo; Felipe Fernandes Conti; Katia De Angelis; Maria Cristina Chavantes
Related Documents :
18543385 - The cardiovascular depression caused by bee venom in sprague-dawley rats associated wit...
25300285 - Effects of 12 weeks treatment with fermented milk on blood pressure, glucose metabolism...
8483795 - The peripheral modulation of duodenal and colonic motility in rats by the pancreatic po...
19871095 - The effect of tyrosinase on experimental hypertension.
2735385 - Deflation opening pressure of the eustachian tube.
8404705 - The effect of midazolam on motility of the sphincter of oddi in human subjects.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arquivos brasileiros de cardiologia     Volume:  103     ISSN:  1678-4170     ISO Abbreviation:  Arq. Bras. Cardiol.     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-09-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421031     Medline TA:  Arq Bras Cardiol     Country:  Brazil    
Other Details:
Languages:  eng; por     Pagination:  161-4     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Debranching solutions in endografting for complex thoracic aortic dissections.
Next Document:  Absence of interaction of diabetes mellitus with chronic kidney disease on mortality in acute heart ...