Document Detail


Hemodynamic controller for left ventricular assist device based on pulsatility ratio.
MedLine Citation:
PMID:  17298400     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hemodynamic control of left ventricular assist devices (LVADs) is generally a complicated problem due to diverse operating environments and the variability of the patients: both the changes in the circulatory and metabolic parameters as well as disturbances that require adjustment to the operating point. This challenge is especially acute with control of turbodynamic blood pumps. This article presents a pulsatility ratio controller for LVAD that provides a proper perfusion according to the physiological demands of the patient, while avoiding adverse conditions. It utilizes the pulsatility ratio of the flow through the pump and pressure difference across the pump as a control index and adjusts the pump speed according to the reference pulsatility ratio under the different operating conditions. The simulation studies were performed to evaluate the controller in consideration of the sensitivity to afterload and preload, influence of the contractility, and effect of suction sensitivity. The controller successfully adjusts the pump speed according to the reference pulsatility ratio, and supports the natural heart under diverse pump operating conditions. The resulting safe pump operations demonstrate the solid performance of the controller in terms of sensitivity to afterload and preload, influence of the contractility, and effect of suction sensitivity.
Authors:
Seongjin Choi; J Robert Boston; James F Antaki
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Artificial organs     Volume:  31     ISSN:  0160-564X     ISO Abbreviation:  Artif Organs     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-02-14     Completed Date:  2007-04-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  114-25     Citation Subset:  IM    
Affiliation:
Department of Electronics and Information Engineering, Korea University, Jochiwon, Chungnam, Korea. choisj@korea.ac.kr
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MeSH Terms
Descriptor/Qualifier:
Equipment Design
Fuzzy Logic
Heart-Assist Devices*
Hemorheology
Humans
Models, Cardiovascular*
Pulsatile Flow / physiology*
Ventricular Pressure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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