Document Detail

Hemodynamic characteristics during treadmill and bicycle exercise in chronic heart failure: mechanism for different responses of peak oxygen uptake.
MedLine Citation:
PMID:  10614842     Owner:  NLM     Status:  MEDLINE    
The exercise capacity of patients with chronic heart failure (CHF) is greater when assessed by the treadmill rather than the bicycle ergometer, but the mechanism of this difference has not been clarified. The present study aimed to determine the difference between the hemodynamics of these exercise modes and the mechanism underlying the different peak oxygen uptake (VO2). Patients (n = 18) underwent a bicycle test and treadmill test using individual ramp protocols. Respiratory gas analysis and hemodynamic measurements with an opti-catheter were performed during both exercise tests. The peak VO2 was significantly larger in the treadmill test than the bicycle test (1410+/-292 vs. 1630+/-331 ml/min, p<0.001). Both the peak cardiac output (Q; 10.2+/-2.2 vs. 10.9+/-2.1 L/min, p<0.001) and the peak arteriovenous oxygen difference (a-v 02 diff; 13.9+/-1.5 vs. 15.0+/-1.2 vol%, p<0.001) were also significantly higher in the treadmill test. The relative contribution of Q and a-v O2 diff to the increased peak VO2 was equivalent, which suggests that both Q and a-v O2 diff. Contribute equally to the different peak VO2 responses in CHF.
S Kim; H Yamabe; M Yokoyama
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  63     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2000-01-27     Completed Date:  2000-01-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  965-70     Citation Subset:  IM    
First Department of Internal Medicine, Kobe University School of Medicine, Japan.
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MeSH Terms
Cardiac Output / physiology
Exercise Test*
Exercise Tolerance
Heart Failure / physiopathology*
Hemodynamics / physiology*
Middle Aged
Oxygen / blood
Oxygen Consumption*
Reproducibility of Results
Reg. No./Substance:

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