| Hemodynamic aspects of mitral regurgitation assessed by generalized phase-contrast MRI. | |
| | |
MedLine Citation:
|
PMID: 21563241 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
PURPOSE: To investigate the utility of MRI measurement of left atrial (LA) flow patterns and turbulent kinetic energy (TKE) in patients with clinically significant mitral regurgitation. MATERIALS AND METHODS: Three-dimensional cine phase-contrast MRI (PC-MRI) data were acquired in five patients with posterior mitral leaflet prolapse and two normal volunteers. LA flow patterns were assessed using particle trace visualization. Specifically, vortices were recognized by closed streamlines. LA flow distortion was assessed by estimation of TKE. In addition, the regurgitant volume was measured. RESULTS: Four of the mitral regurgitation patients had eccentric regurgitant jets directed toward the septum; one patient had a central jet. The dominant systolic vortex was located in proximity to the regurgitant jet. The LA flow was highly disturbed with elevated values of TKE; peak LA TKE ranged from 13 to 37 mJ and occurred consistently at late systole. The average LA TKE per cardiac cycle was significantly related to the regurgitant volume (TKE = 0.573 + 0.179·RegVol, R(2) = 0.983). CONCLUSION: MRI permits investigations of atrial flow patterns and TKE in significant mitral regurgitation. The degree of LA flow distortion, as measured by the average LA TKE over one cardiac cycle, appears to reflect the severity of regurgitation. J. Magn. Reson. Imaging 2011;33:582-588. © 2011 Wiley-Liss, Inc. |
| | |
Authors:
|
Petter Dyverfeldt; John-Peder Escobar Kvitting; Carl Johan Carlhäll; Gabriella Boano; Andreas Sigfridsson; Ulf Hermansson; Ann F Bolger; Jan Engvall; Tino Ebbers |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of magnetic resonance imaging : JMRI Volume: 33 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2011 Mar |
Date Detail:
|
Created Date: 2011-05-12 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
|
Languages: eng Pagination: 582-8 Citation Subset: IM |
Copyright Information:
|
Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
|
Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden; Division of Applied Thermodynamics and Fluid Mechanics, Department of Management and Engineering, Linköping University, Linköping, Sweden; Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden. petter.dyverfeldt@liu.se. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cyclic CINE-balanced steady-state free precession image intensity variations: Implications for the d...
Next Document: In vivo three-dimensional MR wall shear stress estimation in ascending aortic dilatation.