Document Detail

Hemodynamic stress echocardiography in patients supported with a continuous-flow left ventricular assist device.
MedLine Citation:
PMID:  20705267     Owner:  NLM     Status:  MEDLINE    
Functional assessment of continuous-flow left ventricular assist devices (LVADs) is usually performed with the patient at rest. This study compared echocardiographic indices of contraction and filling pressure with invasive measures in 12 ambulatory LVAD patients undergoing symptom-limited bicycle exercise. Exercise induced an increase in cardiac output, systolic pulmonary artery pressure, and diastolic pulmonary artery pressure. Although no changes in left ventricular dimensions or fractional shortening were seen on echocardiography, systolic mitral annular motion (S') increased significantly (in parallel with cardiac output) and diastolic E/e' ratio decreased (correlating inversely with diastolic pulmonary artery pressure). These findings emphasize the potential role of exercise echocardiography in studying exercise hemodynamics in LVAD patients.
Mads Andersen; Finn Gustafsson; Per Lav Madsen; Patrice Brassard; Anette Schophuus Jensen; Niels Secher; Christian Hassager; Nikolai Nordsborg; Jacob Eifer Møller
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  JACC. Cardiovascular imaging     Volume:  3     ISSN:  1876-7591     ISO Abbreviation:  JACC Cardiovasc Imaging     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-13     Completed Date:  2010-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101467978     Medline TA:  JACC Cardiovasc Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  854-9     Citation Subset:  IM    
Department of Cardiology, The Heart Center, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
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MeSH Terms
Blood Pressure
Cardiac Output
Echocardiography, Doppler*
Echocardiography, Doppler, Pulsed
Echocardiography, Stress*
Heart Failure / physiopathology,  therapy*,  ultrasonography
Heart-Assist Devices*
Middle Aged
Mitral Valve / physiopathology,  ultrasonography
Myocardial Contraction
Predictive Value of Tests
Prosthesis Design
Pulmonary Artery / physiopathology,  ultrasonography
Severity of Illness Index
Ventricular Function, Left*
Ventricular Pressure
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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