Document Detail


Hemodilution -- new clothes for an anemic emperor.
MedLine Citation:
PMID:  386607     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This review deals with the rationale for the use of hemodilution in patients not subjected to open heart surgery. The claim for an optimum of circulatory oxygen transport at 30% hematocrit has been disproved; hemodilution thus simply means acute normovolemic anemia. Accordingly, it generates a cardiovascular strain and particularly jeopardizes cerebral and myocardial oxygen supply. Potentially serious clinical side effects have been reported. Hemodilution should therefore not be carried beyong the lower normal range for the hemoglobin or hematocrit level, i.e. 12--12.5 g% or 35--36%.
Authors:
P Lundsgaard-Hansen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Vox sanguinis     Volume:  36     ISSN:  0042-9007     ISO Abbreviation:  Vox Sang.     Publication Date:  1979  
Date Detail:
Created Date:  1979-12-20     Completed Date:  1979-12-20     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0413606     Medline TA:  Vox Sang     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  321-36     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Anemia / complications,  etiology*,  physiopathology
Animals
Blood Volume
Cardiac Output
Coronary Circulation / drug effects
Coronary Disease / physiopathology
Dogs
Hematocrit
Hemodilution / adverse effects*
Humans
Oxygen / metabolism
Physical Exertion
Postoperative Period
Pulmonary Edema / etiology
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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