Document Detail


Hemodialysis versus peritoneal dialysis: a case control study of survival in patients with chronic kidney disease stage 5.
MedLine Citation:
PMID:  19527466     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It is still controversial whether the mode of dialysis or preexisting comorbidities may influence the prognosis of patients with chronic kidney disease stage 5. Therefore, we performed a prospective case control study to evaluate whether the mode of dialysis may influence outcome. We found 25 cases on peritoneal dialysis (PD) treatment and 75 age and sex-matched controls on hemodialysis (HD) treatment for more than 3 months. Analysis was by intention-to-treat. During the follow up of 58 months, 6 out of 25 patients (24%) died in the PD group, whereas in the HD group 26 out of 75 patients (35%) died (relative risk 0.69 [95% CI 0.32 to 1.49]; P = 0.46). Survival was not significantly different between the groups as indicated by Mantel-Cox log-rank test (hazard ratio 0.52 [95% CI 0.25 to 1.10]; P = 0.11). Multiple variable regression showed that age and diabetes mellitus, but not mode of dialysis, predicted death in patients with chronic kidney disease. It is concluded that age and comorbidities but not mode of dialysis are important to predict survival in patients with chronic kidney disease stage 5.
Authors:
Alexandra Maier; Franziska Stocks; Wolfgang Pommer; Walter Zidek; Martin Tepel; Alexandra Scholze
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy     Volume:  13     ISSN:  1744-9987     ISO Abbreviation:  Ther Apher Dial     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-16     Completed Date:  2009-08-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101181252     Medline TA:  Ther Apher Dial     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  199-204     Citation Subset:  IM    
Affiliation:
Department of Nephrology, Charité University Medical School, Hindenburgdamm 30, Berlin, Germany.
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Case-Control Studies
Diabetes Mellitus / physiopathology
Female
Follow-Up Studies
Humans
Kidney Failure, Chronic / complications,  mortality,  therapy*
Male
Middle Aged
Peritoneal Dialysis / methods*,  mortality
Proportional Hazards Models
Prospective Studies
Regression Analysis
Renal Dialysis / methods*,  mortality
Survival Rate
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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