Document Detail

Hemodialysis duration impairs food intake and nutritional parameters in chronic kidney disease patients.
MedLine Citation:
PMID:  21104434     Owner:  NLM     Status:  In-Data-Review    
INTRODUCTION: The aim of this study was to evaluate the effect of hemodialysis (HD) duration on food intake and nutritional markers in patients with chronic kidney disease (CKD).
METHODS: Twenty CKD patients received maintenance HD over a 9-year period. At the beginning of the study (T0) and at 3-year intervals (T1, T2, and T3) during the 9-year follow-up, a nutritional survey using the 24-h recall and record method was repeated for 4 days, and the blood samples were drawn. The results from T0 were used as references. Nutritional status was assessed through food intake, nutritional markers (urea, uric acid, creatinine, cholesterol, total protein, and albumin), and anthropometric measurements (height, dry weight, and body mass index).
RESULTS: HD duration was correlated with energy intake (r = -0.89, P < 0.01), protein intake (r = -0.50, P < 0.05), and body mass index (r = -0.50, P < 0.05). Albuminemia decreased over time. Reduced carbohydrate intakes were noted in patients at T1 (-8%), T2 (-38%), and T3 (-59%) with decreased fiber intakes. Lipid intake was diminished by 11, 17, and 25% in patients, respectively, at T1, T2, and T3. The consumption of milk and dairy products, meats, fish, eggs, fruits, vegetables, and fat was reduced at T1, T2, and T3. In conclusion, long-term HD fails to correct undernutrition caused by CKD. Long-term dialysis complications could be reduced with preventive measures, including the use of biocompatible membranes and high-dose dialysis. Consequently, patients could experience a decreased prevalence of protein-energy malnutrition.
Khedidja Mekki; Mustapha Remaoun; Jacques Belleville; Malika Bouchenak
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Publication Detail:
Type:  Journal Article     Date:  2010-11-23
Journal Detail:
Title:  International urology and nephrology     Volume:  44     ISSN:  1573-2584     ISO Abbreviation:  Int Urol Nephrol     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0262521     Medline TA:  Int Urol Nephrol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  237-44     Citation Subset:  IM    
Laboratoire de Nutrition Clinique et Métabolique, Département de Biologie. Faculté des Sciences, Université d'Oran, 31100, Es-Sénia, Algeria,
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