Document Detail


Hemiextinction induced by transcranial magnetic stimulation over the right temporo-parietal junction.
MedLine Citation:
PMID:  16876326     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Whereas it is widely accepted that the parietal cortex is crucial for visual attention, the role of the temporal cortex and the temporo-parietal junction (TPJ) is less clear. There are clinical reports of patients with lesions in different posterior temporal areas which exhibit contralateral visual neglect but this syndrome seems to be less frequent than in patients with parietal lesions. In a previous study, we could show that single-pulse transcranial magnetic stimulation (TMS) over the right inferior parietal cortex is capable to induce both neglect-like and extinction-like impairments of performance in normal subjects. In the present study, we used this method to examine the functional role of the superior temporal gyrus (STG) and the TPJ of the right hemisphere for visuo-spatial attention. Healthy volunteers were asked to detect small dots appearing for 40 ms unilaterally on right or left side or bilaterally on a computer screen. TMS was applied over the TPJ or STG. TMS over the TPJ induced an extinction-like behavioral pattern to the contralateral hemifield. TMS over the STG had no effect. The results demonstrate a functional involvement of the TPJ in visuo-attentional processing of competing stimuli in both hemifields. This region is part of the cortical network mediating stimulus-driven attention which is relevant for processing of competing stimuli.
Authors:
I G Meister; M Wienemann; D Buelte; C Grünewald; R Sparing; N Dambeck; B Boroojerdi
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-07-28
Journal Detail:
Title:  Neuroscience     Volume:  142     ISSN:  0306-4522     ISO Abbreviation:  Neuroscience     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-09-18     Completed Date:  2006-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7605074     Medline TA:  Neuroscience     Country:  United States    
Other Details:
Languages:  eng     Pagination:  119-23     Citation Subset:  IM    
Affiliation:
Department of Neurology, RWTH Aachen University, Pauwelsstr. 30, 52074 Aachen, Germany. igmeister@gmx.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Attention / physiology
Female
Frontal Lobe / physiopathology*
Functional Laterality / physiology*
Humans
Male
Parietal Lobe / physiopathology*
Perceptual Disorders / etiology*
Photic Stimulation / methods
Space Perception / physiology
Transcranial Magnetic Stimulation / adverse effects*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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