| Hemiballism with insular infarction as first manifestation of Takayasu's arteritis in association with chronic hepatitis B. | |
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MedLine Citation:
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PMID: 12574956 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Takayasu's arteritis is a chronic inflammatory idiopathic disease involving large arteries like the aorta and its primary branches. Cell-mediated autoimmunity leading to vascular injury has been suspected in its pathogenesis although the antigen inducing the process remains unknown. CASE REPORT: A 50-year-old male patient suffered from acute hemiballism. Neuroimaging showed an infarction of right temporal insular cortex. Neurosonology and MR-Angiography revealed bilateral long-distant subtotal stenosis of the common carotid artery and left-sided occlusion of the subclavian artery. Positive hepatitis B serology with active viral replication was found. In the absence of other vasculitis or inflammation markers, Takayasu's arteritis was diagnosed and steroid therapy was started. CONCLUSIONS: Unilateral insular lesions may lead to transient hemiballistic movements which could be the result of decreased inhibitory output of the insula to basal ganglia. The hepatitis B virus possibly contains a surface antigen inducing a specific cellular immune response leading to Takayasu's arteritis. |
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Authors:
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Thorleif Etgen; Kerstin Winbeck; Bastian Conrad; Dirk Sander |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of neurology Volume: 250 ISSN: 0340-5354 ISO Abbreviation: J. Neurol. Publication Date: 2003 Feb |
Date Detail:
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Created Date: 2003-02-07 Completed Date: 2003-04-03 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0423161 Medline TA: J Neurol Country: Germany |
Other Details:
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Languages: eng Pagination: 226-9 Citation Subset: IM |
Affiliation:
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Department of Neurology, Technical University of Munich, Möhlstrasse 28, 81675 München, Germany. etgen@neuro.med.tu-muenchen.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Inflammatory Agents
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therapeutic use Brain Ischemia / pathology Carotid Stenosis / pathology Cerebral Infarction / etiology*, pathology, ultrasonography Dyskinesias / etiology*, ultrasonography Hepatitis B, Chronic / complications*, drug therapy, pathology Humans Magnetic Resonance Angiography Magnetic Resonance Imaging Male Middle Aged Steroids Subclavian Steal Syndrome / pathology Takayasu Arteritis / complications*, drug therapy, pathology Ultrasonography, Doppler, Duplex |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Steroids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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