| Hematological response of pancytopenia to glucocorticoids in patients with Sheehan's syndrome. | |
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MedLine Citation:
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PMID: 21424753 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Sheehan's syndrome presents with panhypopituitarism after childbirth, usually preceded by post partum hemorrhage. Hematological abnormalities like pancytopenia with hypocellular marrow in these patients are reported rarely. Though multiple hormone deficiencies may contribute to Pancytopenia in Sheehan's syndrome, complete recovery is observed after achieving eucortisolemic and euthyroid state. The predominant role of thyroxine or glucocorticoids in reversing pancytopenia in these patients has not been studied. We present the clinical, hormonal, hematological course and response to glucocorticoids in a patient of Sheehan's syndrome presenting with pancytopenia. Complete recovery of pancytopenia was observed after achieving eucortisolemic state thus concluding that gulcocorticoid replacement is sufficient to reverse pancytopenia in these patients. |
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Authors:
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Bashir Ahmad Laway; Shahnaz Ahmad Mir; Javid Rasool Bhat; Mohd Iqbal Lone; Jeelani Samoon; Abdul Hamid Zargar |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-3-22 |
Journal Detail:
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Title: Pituitary Volume: - ISSN: 1573-7403 ISO Abbreviation: - Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-3-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9814578 Medline TA: Pituitary Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Endocrinology, Sher-I- Kashmir Institute of Medical Sciences Soura, Srinagar, Jammu and Kashmir, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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