Document Detail


Hematological manifestations of congenital cytomegalovirus infection.
MedLine Citation:
PMID:  10829908     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nine infants suffering from congenital cytomegalovirus infection were studied for clinical features with special reference to hematological manifestations. The mean age of appearance of first clinical symptom of disease was 14 days and mean age at presentation was 58 days. Significant pallor, thrombocytopenia and evidence of hemolysis were present in 8 (89%), 4 (44%) and 4 (44%) patients respectively out of three bone marrow examination performed, paucity of erythroid and megakaryocytic cells were seen in two. The other clinical features included hepatomegaly in a (100%) splenomegaly in 6 (66%) each, petachial rash in 5 (55%), Hepatitis in 4 (44%) optic atrophy and corneal opacities in one patient each. Two patients died. Remaining patients showed symptomatic improvement without specific therapy.
Authors:
H K Pemde; S K Kabra; R Agarwal; Y Jain; V Seth
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  62     ISSN:  0019-5456     ISO Abbreviation:  Indian J Pediatr     Publication Date:    1995 Jul-Aug
Date Detail:
Created Date:  2000-06-21     Completed Date:  2000-06-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  473-7     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi.
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MeSH Terms
Descriptor/Qualifier:
Cytomegalovirus Infections / congenital*,  diagnosis*,  mortality
Female
Hematologic Diseases / mortality,  physiopathology*,  virology*
Humans
India
Infant, Newborn
Male
Prognosis
Severity of Illness Index
Survival Analysis

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