| Hematological abnormalities in scleroderma. A study of 180 cases. | |
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MedLine Citation:
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PMID: 6774574 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hematological abnormalities in scleroderma indicate a specific complication of the disease itself, or an associated illness. Among 180 patients with scleroderma, anemia was detected in 25% and was attributed to chronic inflammatory disease (usually an overlap syndrome), bleeding mucosal telangiectases as part of the CREST syndrome, intestinal malabsorption, and microangiopathic hemolysis. Leukocytosis, present in 14%, was correlated with active myopathy and/or advanced visceral involvement while leukopenia was suggestive of a crossover with systemic lupus erythematosus. Thrombocytopenia was often a manifestation of microangiopathy, and thrombocytosis was associated with an arteritis or a tumor syndrome. |
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Authors:
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R A Frayha; L E Shulman; M B Stevens |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta haematologica Volume: 64 ISSN: 0001-5792 ISO Abbreviation: Acta Haematol. Publication Date: 1980 |
Date Detail:
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Created Date: 1980-11-25 Completed Date: 1980-11-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0141053 Medline TA: Acta Haematol Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 25-30 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia
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etiology Blood Cell Count Female Hematologic Diseases / etiology* Humans Leukocytosis / etiology Leukopenia / etiology Male Scleroderma, Systemic / blood, complications* Thrombocytopenia / etiology Thrombocytosis / etiology |
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