Document Detail

Hematologic study of newborn umbilical cord blood.
MedLine Citation:
PMID:  10684163     Owner:  NLM     Status:  MEDLINE    
Hematological parameters in newborn umbilical cord blood samples (n = 476), collected at the Hospital Provincial del Centenario, Rosario, were studied. They were divided into 3 groups: (I) full term newborns with weight according to gestational age; (II) low weight and normal gestational age; (III) preterm newborns. The results were as follows: group (I) Hb: 15.5 +/- 1.1 g/dl; RBC; 4.66 +/- 0.33 x 10(12)/l; PCV: 49% +/- 4.3%, MCV 105.1 +/- 5.3 fl; MHC: 33.2 +/- 1.2 pg. Decreased Hb concentration (p < 0.05) and increased MCV (p < 0.01) were observed in preterm newborns in comparison with normal ones, and a slight PCV increase and RBC values in low weight newborns compared to the control group (p < 0.05). Erythrocyte morphology was normal as well as reticulocyte values in these samples. The electrophoretic pattern was (FA) with the following Hb F values 66.3 +/- 6.8%, and Hb A2 0.45 +/- 0.3% in group (I), with a significant increase of Hb F in 30-35 weeks preterm newborns. Group (I) values are considered as normal hematological parameters in newborns in our country, whereas MCV < 94.7 fl is considered as a neonatal microcytosis marker, consequently an alert to investigate alpha-thalassemia. There was no influence on Hb concentration due to maternal smoking habit. The present work could be of relevance for our region since up to the present time there are no similar records.
N I Noguera; G Detarsio; S M Pérez; I M Bragós; O Lanza; J H Rodríguez; I Acosta; R Davoli; A C Milani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicina     Volume:  59     ISSN:  0025-7680     ISO Abbreviation:  Medicina (B Aires)     Publication Date:  1999  
Date Detail:
Created Date:  2000-03-20     Completed Date:  2000-03-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0204271     Medline TA:  Medicina (B Aires)     Country:  ARGENTINA    
Other Details:
Languages:  eng     Pagination:  446-8     Citation Subset:  IM    
Departamento Bioquímica Clínica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Argentina.
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MeSH Terms
Erythrocyte Indices
Fetal Blood / chemistry*
Fetal Hemoglobin / analysis
Hemoglobin A2 / analysis
Hemoglobins / analysis
Infant, Newborn
Infant, Premature / blood
Prospective Studies
Reg. No./Substance:
0/Hemoglobins; 9034-53-1/Hemoglobin A2; 9034-63-3/Fetal Hemoglobin

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