Document Detail


Hematologic studies during isolated ultrafiltration.
MedLine Citation:
PMID:  7249428     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of negative-pressure isolated ultrafiltration on leucocytes, platelets, and clotting factors was evaluated in maintenance hemodialysis patients. A significant decrease in the number of leucocytes was observed during the first 45 minutes of ultrafiltration. However, by one hour, leucocyte counts had returned to pre-ultrafiltration values. A slight, of haptoglobin, free hemoglobin, or fibrinogen after one hour of isolated ultrafiltration. Levels of fibrin degradation products and fibrin monomers similarly showed no change. Heparin administration alone had no effect on the above hematologic values. We suggest that isolated ultrafiltration, as clinically practised, has little acute effect on the coagulation system, and does not cause detectable hemolysis. The transient decrease in leucocyte count, and the modest fall in platelet count that were found are in keeping with changes previously reported to occur during hemodialysis.
Authors:
T S Ing; W T Chen; D V Weber; J T Daugirdas; R M Vilbar; J E Hano; H C Kwaan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  15     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1981 Jun 
Date Detail:
Created Date:  1981-09-22     Completed Date:  1981-09-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  299-301     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Blood*
Blood Coagulation Factors / analysis*
Humans
Kidney Diseases / blood*,  therapy
Leukocyte Count*
Platelet Count*
Renal Dialysis
Ultrafiltration*
Chemical
Reg. No./Substance:
0/Blood Coagulation Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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