Document Detail

Hematologic status in recurrent aphthous stomatitis compared with other oral disease.
MedLine Citation:
PMID:  3165514     Owner:  NLM     Status:  MEDLINE    
The hematologic status of 144 consecutive patients in the United Kingdom with oral disease (69 with recurrent aphthous stomatitis; 75 with other disorders) was examined in an attempt to resolve the controversy as to whether levels of hemoglobin, blood cell numbers and indices, and blood film are adequate in the screening of patients with aphthae. Though hemoglobin levels and red blood cell indices were normal in patients with recurrent aphthous stomatitis, there was still a small minority of patients with deficiencies of iron (low serum ferritin), folate (low red blood cell levels), or vitamin B12 (low serum levels) that would have remained undetected. Full hematologic screening of patients with recurrent aphthous stomatitis thus reveals latent deficiency states, at least in some parts of the world, and there are good reasons for elucidating the underlying cause and correcting these deficiencies, particularly vitamin B12 deficiency. Therapeutic studies are now required to establish the frequency with which deficiencies actually predispose to recurrent aphthous stomatitis.
S R Porter; C Scully; S Flint
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, and oral pathology     Volume:  66     ISSN:  0030-4220     ISO Abbreviation:  Oral Surg. Oral Med. Oral Pathol.     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-09-20     Completed Date:  1988-09-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376406     Medline TA:  Oral Surg Oral Med Oral Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  41-4     Citation Subset:  D; IM    
University Department of Oral Medicine, Surgery, and Pathology, Bristol Dental Hospital and School, England.
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MeSH Terms
Erythrocyte Indices
Erythrocytes / analysis
Ferritins / blood
Folic Acid / blood
Mouth Diseases / blood*
Stomatitis, Aphthous / blood*
Vitamin B 12 / blood
Reg. No./Substance:
59-30-3/Folic Acid; 68-19-9/Vitamin B 12; 9007-73-2/Ferritins

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