Document Detail

Hematologic complications of HIV infection.
MedLine Citation:
PMID:  16425959     Owner:  NLM     Status:  MEDLINE    
Treatment of HIV-infected patients with highly active antiretroviral therapy (HAART) has altered the natural history of human immunodeficiency virus (HIV) infection by decreasing the frequency of opportunistic infections and altering the expected frequency of hematologic complications and AIDS-related malignancies. Thrombotic thrombocytopenic purpura and thrombosis resulting from protein S deficiency are relatively rare complications of HIV in the United States in patients taking HAART, but are frequent in the developing world where these drugs are not available. Cytopenia, particularly anemia, are more common and result both from bone marrow failure and peripheral destruction. Hodgkin's and non-Hodgkin's lymphoma are still problematic in patients with advanced disease with high viral loads. This review will examine and discuss the diagnosis and management of the hematologic complications of HIV.
Elaine Sloand
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  AIDS reviews     Volume:  7     ISSN:  1139-6121     ISO Abbreviation:  AIDS Rev     Publication Date:    2005 Oct-Dec
Date Detail:
Created Date:  2006-01-23     Completed Date:  2006-02-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101134876     Medline TA:  AIDS Rev     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  187-96     Citation Subset:  IM    
Hematology Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Building 10 CRC 4E Rm 5230, Bethesda, Md, USA.
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MeSH Terms
Anemia / drug therapy,  etiology
Antiretroviral Therapy, Highly Active
HIV Infections / complications*,  drug therapy
Hematologic Diseases / drug therapy,  etiology*
Lymphoma, AIDS-Related / drug therapy,  etiology
Neutropenia / drug therapy,  etiology

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