Document Detail

Hematologic and biochemical laboratory parameters before and after a marathon race.
MedLine Citation:
PMID:  12953147     Owner:  NLM     Status:  MEDLINE    
Marathon racing is a strenuous exercise that has a profound effect on many laboratory parameters. Participants in marathon races may require abstinence of exercise and the performance of laboratory assays several days after the event. The aim of this study was to evaluate the possible changes in blood cell count and biochemical parameters observed in participants in a marathon 3 days before and 3 days after and before and immediately after a cardiopulmonary exercise test. Incremental cycle ergometry up to maximal capacity was performed in 7 marathon runners, 3 days before and 3 days after the race. The % peak oxygen consumption (peak %VO(2)) achieved was statistically significantly lower after than before the race ( p = 0.02). No statistically significant differences were observed in cardiac frequency ( p = 0.148) or blood cell count ( p = 0.501). Also, the concentration of sodium, potassium, calcium, magnesium, lactate dehydrogenase (LDH), phosphocreatine kinase (CPK) and glucose, measured before and immediately after the pulmonary exercise test, did not differ significantly ( p < 0.5). A significant percentage of the laboratory results were outside the standard reference rates. According to our data, exercise performance, as expressed by peak %VO(2), continued to be decreased in marathon runners 3 days after the race. The blood cell count and biochemical parameters did not differ significantly but many marathon runners were outside the standard reference rates. Unfortunately, only 7 subjects were available for this study. Further studies with larger samples and with samples obtained at multiple times during and after exercise are needed to clarify the effects of long-distance running.
K Spiropoulos; G Trakada
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lung     Volume:  181     ISSN:  0341-2040     ISO Abbreviation:  Lung     Publication Date:  2003  
Date Detail:
Created Date:  2003-09-03     Completed Date:  2003-10-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7701875     Medline TA:  Lung     Country:  United States    
Other Details:
Languages:  eng     Pagination:  89-95     Citation Subset:  IM    
Department of Internal Medicine, University Hospital of Patras Medical School, Patras 26500, Greece.
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MeSH Terms
Blood Cell Count
Blood Chemical Analysis
Exercise Test
Exercise Tolerance / physiology*
Oxygen Consumption
Physical Endurance
Reference Values
Running / physiology*
Time Factors

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