Document Detail

Heliotropium europaeum poisoning of sheep with low liver copper concentrations and the preventive efficacy of cobalt and antimethanogen.
MedLine Citation:
PMID:  1316747     Owner:  NLM     Status:  MEDLINE    
In a field experiment in the Mallee district of Victoria, Merlno xBorder Leicester ewes and wethers grazed Heliotropium europaeum (heliotrope) over periods of 3 to 4 months in 4 successive years. By the end of the second year 12% (14 of 120) of the sheep had died; after 4 years the loss attributable to heliotrope was between 18% and 35%. Mortality was not affected by intraruminal treatment with cobalt or antimethanogen. At the end of the experiment the highest concentration of copper in the liver was 1.95 mmol/kg wet weight (approximately 413 micrograms/g dry weight). The relatively low mortality from primary heliotrope poisoning and the low concentration of copper in the liver of sheep grazing the plant are discussed in relation to the contrasting situation that prevails in the Riverina area of New South Wales. The importance of local environmental factors in the management of heliotrope grazing by sheep is emphasised, particularly in relation to the number of seasons in which the plant may be a major component of the diet.
J E Peterson; A Payne; C C Culvenor
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Australian veterinary journal     Volume:  69     ISSN:  0005-0423     ISO Abbreviation:  Aust. Vet. J.     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-06-16     Completed Date:  1992-06-16     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370616     Medline TA:  Aust Vet J     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  51-6     Citation Subset:  IM    
CSIRO Division of Animal Health, Animal Health Research Laboratory, Parkville, Victoria.
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MeSH Terms
Alkanesulfonates / therapeutic use*
Alkanesulfonic Acids*
Body Weight
Cobalt / therapeutic use*
Copper / analysis
Kidney / pathology
Liver / chemistry,  pathology
Liver Function Tests / veterinary
Plant Poisoning / mortality,  prevention & control,  veterinary*
Poaceae / chemistry
Sheep Diseases / mortality,  pathology,  prevention & control*
Reg. No./Substance:
0/Alkanesulfonates; 0/Alkanesulfonic Acids; 26978-65-4/2-bromoethanesulfonic acid; 7440-48-4/Cobalt; 7440-50-8/Copper

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