| Helicobacter pylori and recurrent pain abdomen. | |
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MedLine Citation:
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PMID: 16077238 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Pain abdomen is a common problem in childhood. Many factors i.e., organic changes in the gut, psychological and environment contribute to recurrent pain abdomen (RAP) in children. Helicobacter pylori infects children very early in childhood and stays indefinitely in the gut without its eradication. It may be responsible for pain abdomen and peptic ulcers in children. This study was done to assess the HP status in children with RAP diagnosed and evaluate the effects of eradication of HP infection in them. METHODS: 76 children were included in the study. RESULT: Out of 76 children studied 14.8% had evidence of a secondary cause for pain abdomen and responded to appropriate therapy. 65.45% of children who had undergone UGIE, had evidence of HP infection in the upper gastrointestinal tract. Most of these children responded to HP eradication therapy by becoming free of abdominal pain after the eradication therapy with OCA or OMA regimen. We could not do repeated endoscopies in all of them to prove the eradication due to parents' refusal and this is the main drawback of this study. CONCLUSION: However, in view of clinical response to HP eradication therapy in almost all the cases, we strongly advocate this therapy for those children with RAP, in whom HP infection of the upper gastrointestinal tract can be established beyond doubt. |
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Authors:
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Niranjan Biswal; N Ananathakrishnan; Vikram Kate; S Srinivasan; P Nalini; Betsy Mathai |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: Indian journal of pediatrics Volume: 72 ISSN: 0973-7693 ISO Abbreviation: Indian J Pediatr Publication Date: 2005 Jul |
Date Detail:
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Created Date: 2005-08-03 Completed Date: 2006-06-13 Revised Date: 2009-07-15 |
Medline Journal Info:
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Nlm Unique ID: 0417442 Medline TA: Indian J Pediatr Country: India |
Other Details:
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Languages: eng Pagination: 561-5 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India. nbiswal@jipmer.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Pain
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etiology* Adolescent Anti-Bacterial Agents / therapeutic use Anti-Ulcer Agents / therapeutic use Child Child, Preschool Endoscopy Female Helicobacter Infections / complications, diagnosis*, drug therapy Helicobacter pylori / isolation & purification* Humans India Male Omeprazole / therapeutic use Peptic Ulcer / complications*, drug therapy, etiology Prospective Studies Recurrence Urease / diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Anti-Ulcer Agents; 73590-58-6/Omeprazole; EC 3.5.1.5/Urease |
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