Document Detail

Helicobacter pylori gastritis in a child with sickle cell anemia and recurrent abdominal pain.
MedLine Citation:
PMID:  9149750     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Recurrent abdominal pain is a common complaint in children with sickle cell disease. Helicobacter pylori gastritis has recently been described in association with recurrent abdominal pain in children.
PATIENTS AND METHODS: A case report is given of a 16-year-old black male with hemoglobin SS disease presenting with recurrent abdominal pain and hematemesis.
RESULTS: Endoscopic exam of the upper gastrointestinal tract revealed gastritis, and biopsy confirmed H. pylori infection. Serology studies demonstrated increased anti-H. pylori antibody titers. The young man responded well to treatment, with resolution of his symptoms.
CONCLUSION: Helicobacter pylori infection is a new diagnostic consideration for children with recurrent abdominal pain and should be included in the differential diagnosis of children with sickle cell disease, especially when abdominal pain is recurrent and accompanied by vomiting. Larger case studies will be necessary to determine the true incidence of H. pylori in children with sickle cell disease and recurrent abdominal pain.
L Kennedy; D H Mahoney; C A Redel
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  19     ISSN:  1077-4114     ISO Abbreviation:  J. Pediatr. Hematol. Oncol.     Publication Date:    1997 Mar-Apr
Date Detail:
Created Date:  1997-06-03     Completed Date:  1997-06-03     Revised Date:  2011-10-06    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  163-4     Citation Subset:  IM    
Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, USA.
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MeSH Terms
Abdominal Pain / complications*
Anemia, Sickle Cell / complications*
Gastritis / complications*,  microbiology,  therapy
Helicobacter Infections / complications*,  microbiology,  physiopathology
Helicobacter pylori / isolation & purification*

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