Document Detail


Helicobacter pylori colonization of tongue mucosa--increased incidence in atrophic glossitis and burning mouth syndrome (BMS).
MedLine Citation:
PMID:  11555160     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nested polymerase chain reaction (PCR) was performed to detect the presence of Helicobacter pylori in tongue mucosa in 268 patients divided into four groups according to their diagnosis: 87 with atrophic glossitis, 37 with benign migratory glossitis and 144 with burning mouth syndrome (BMS). The latter group was subdivided according to anatomic site of burning sensation: subgroup A (54 patients) with complaints limited to tongue and subgroup B (90 patients) with burning sensations in other parts of oral mucosa. H. pylori was found in 43 samples (16%). Bacteria were significantly less present in tongue mucosa affected with benign migratory glossitis compared with atrophic glossitis and BMS (P=0.025). This difference was more obvious when compared with atrophic glossitis only (P=0.006). Mucosal changes in these conditions might make the oral environment more acceptable for H. pylori colonization compared with normal mucosa, and this mechanism may play a role in its oro-oral transmission.
Authors:
K Gall-Troselj; M Mravak-Stipetić; I Jurak; W L Ragland; J Pavelić
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology     Volume:  30     ISSN:  0904-2512     ISO Abbreviation:  J. Oral Pathol. Med.     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-09-13     Completed Date:  2001-12-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8911934     Medline TA:  J Oral Pathol Med     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  560-3     Citation Subset:  D; IM    
Affiliation:
Division of Molecular Medicine, Rudjer Boskovic Institute, 1000 Zagreb, Bijenicka cesta 54, Croatia. troselj@rudjer.irb.hr
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MeSH Terms
Descriptor/Qualifier:
Burning Mouth Syndrome / microbiology*
DNA, Bacterial / analysis
Female
Glossitis / microbiology*
Glossitis, Benign Migratory / microbiology
Helicobacter pylori / isolation & purification*
Humans
Male
Mouth Mucosa / microbiology*
Polymerase Chain Reaction
Chemical
Reg. No./Substance:
0/DNA, Bacterial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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