Document Detail


Helicase translocation assay method using avidin and biotinylated nucleotides.
MedLine Citation:
PMID:  18594773     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Helicase involves many cellular processes that separate double-stranded nucleic acid into single strands. Although it is believed that helicase translocates nucleic acids, it is difficult to show the direct evidence of translocation on nucleic acids. In this study, an avidin-biotinylated nucleotides-based method for helicase translocation assay has been described, and the biochemical assay results have been demonstrated.
Authors:
Jae-Ho Shin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-07-02
Journal Detail:
Title:  Biotechnology letters     Volume:  30     ISSN:  1573-6776     ISO Abbreviation:  Biotechnol. Lett.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-09-23     Completed Date:  2009-01-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008051     Medline TA:  Biotechnol Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  2007-12     Citation Subset:  IM    
Affiliation:
School of Applied Biosciences, Kyungpook National University, Daegu, 702-701, South Korea. jhshin@knu.ac.kr
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MeSH Terms
Descriptor/Qualifier:
Avidin / chemistry,  metabolism*
Biotinylation
DNA Helicases / chemistry,  metabolism*
DNA, Single-Stranded / chemistry,  metabolism
DNA-Directed DNA Polymerase / chemistry,  metabolism
Models, Biological
Nucleotides / chemistry,  metabolism*
Chemical
Reg. No./Substance:
0/DNA, Single-Stranded; 0/Nucleotides; 1405-69-2/Avidin; EC 2.7.7.7/DNA-Directed DNA Polymerase; EC 3.6.1.-/DNA Helicases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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