| Helical tomotherapy for scalp recurrence of primary eccrine mucinous adenocarcinoma. | |
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MedLine Citation:
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PMID: 20210254 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Primary cutaneous mucinous carcinomas originating from sweat glands are rare tumors with patterns of spread that are difficult to predict. We present a case of a five times recurring eccrine mucinous adenocarcinoma of the scalp, previously treated with surgery and adjuvant radiation therapy. After magnetic resonance imaging (MRI) and 18F-fluoro-2-deoxyglucose positron-emission tomography/computed tomography (18FDG-PET/CT), which documented local recurrence, the patient was considered eligible for salvage irradiation of the scalp. We decided to use helical tomotherapy, which combines conformity of dose delivery with the possibility of daily control of the setup accuracy. Forty gray (2Gy/fraction) to the planning target volume and 50 Gy (2.5Gy/fraction) to the biological target volume defined on the basis of 18FDG-PET/CT was prescribed with a simultaneous integrated boost technique. After 12 fractions the patient was submitted to intermediate evaluation by 18FDG-PET/CT, which showed a partial response to the treatment. After 2, 4, 8, and 12 months, 18FDG-PET/CT showed a complete metabolic local response. This experience suggests a possible role of 18FDG-PET/CT-guided helical tomotherapy as an alternative to repeated and frequently demolitive surgery approaches. |
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Authors:
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Micaela Motta; Filippo Alongi; Elena De Martin; Claudio Fiorino; Eleonora Maggiulli; Lara Rigoni; Claudio Landoni; Sara Broggi; Aniko Maria Deli; Riccardo Calandrino; Nadia Di Muzio |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Tumori Volume: 95 ISSN: 0300-8916 ISO Abbreviation: Tumori Publication Date: 2009 Nov-Dec |
Date Detail:
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Created Date: 2010-03-08 Completed Date: 2010-03-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0111356 Medline TA: Tumori Country: Italy |
Other Details:
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Languages: eng Pagination: 832-5 Citation Subset: IM |
Affiliation:
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Radiotherapy Department, Scientific Institute San Raffaele, Milan, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma, Mucinous
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diagnosis,
radiotherapy* Aged Dose Fractionation Female Head and Neck Neoplasms / diagnosis, radiotherapy* Humans Neoplasm Recurrence, Local / diagnosis, radiotherapy* Positron-Emission Tomography Salvage Therapy / methods Scalp Sweat Gland Neoplasms / diagnosis, radiotherapy* Tomography, Spiral Computed* / methods Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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