| Heel skin hyperaemia: direct compression versus vascular occlusion. | |
| | |
MedLine Citation:
|
PMID: 14617267 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Vulnerability of the heel to ulceration in bed-bound persons is related to direct pressure-induced blood flow decreases. Periodic pressure reduction is a clinical strategy to help prevent ulcers by allowing flow-repayment hyperaemia that has a magnitude and duration thought to be related to the duration of the prior interval of ischaemia. However, there are reasons to question whether effects of flow stoppages caused by direct tissue loading are similar to those because of ischaemia without superimposed direct pressure. This question was investigated by comparing posterior heel skin blood flow responses via laser-Doppler perfusion monitoring of 27 supine-lying subjects in whom blood flow was reduced by 5-min of direct heel loading on a support surface and by 5-min of ankle-cuff compression. Results showed that blood flow reductions were the same for both methods but the hyperaemia was significantly greater when flow reduction was produced by direct heel loading. This was true for ratio of peak hyperaemic flow to baseline (8.20 +/- 1.32 s versus 4.68 +/- 0.80 s, P< or =0.001), hyperaemic to baseline 3-min flow-time area ratios (4.70 +/- 0.65 s versus 1.95 +/- 0.29 s, P< or =0.001) and for total hyperaemia durations (352 +/- 39 s versus 181 +/- 14 s, P<0.001). These findings raise new questions regarding the precise physiological effects of heel and tissue loading in general, the factors that contribute to the hyperaemic response and their clinical impact and interpretation. Possible sources of the observed greater post-loading hyperaemia responses are discussed. |
| | |
Authors:
|
Harvey N Mayrovitz; Nancy Sims; Lori Dribin |
Related Documents
:
|
8748887 - Advances in microcirculation network evaluation: an update. 14713127 - Hypoxic regulation of blood flow in humans. skin blood flow and temperature regulation. 1537947 - Chemical peeling of eyelids and periorbital area. 11897477 - Cutaneous blood flow and thermoregulation in prader-willi syndrome patients. 9320017 - Consequences of catecholamine release on ventilation and blood oxygen transport during ... 3318017 - Malaria and loaisis among blood donors at ibadan, nigeria. |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
Journal Detail:
|
Title: Clinical physiology and functional imaging Volume: 23 ISSN: 1475-0961 ISO Abbreviation: Clin Physiol Funct Imaging Publication Date: 2003 Nov |
Date Detail:
|
Created Date: 2003-11-17 Completed Date: 2004-07-06 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 101137604 Medline TA: Clin Physiol Funct Imaging Country: England |
Other Details:
|
Languages: eng Pagination: 354-9 Citation Subset: IM |
Affiliation:
|
College of Medical Sciences, Nova Southeastern University, Ft Lauderdale, FL 33328, USA. mayrovit@comcast.net |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Bandages Blood Flow Velocity Female Heel / blood supply*, physiopathology* Humans Hyperemia / physiopathology* Male Microcirculation / physiopathology* Middle Aged Pressure Regional Blood Flow Skin / blood supply*, physiopathology* Vasoconstriction* Weight-Bearing* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Injurious ventilation strategies cause systemic release of IL-6 and MIP-2 in rats in vivo.
Next Document: Tacrolimus inhibits discordant islet xenograft rejection: a study in the pig-to-rat model.