Document Detail

Hedgehog signaling and maintenance of homeostasis in the intestinal epithelium.
MedLine Citation:
PMID:  22689790     Owner:  NLM     Status:  In-Data-Review    
Homeostasis of the rapidly renewing intestinal epithelium depends on a balance between cell proliferation and loss. Indian hedgehog (Ihh) acts as a negative feedback signal in this dynamic equilibrium. We discuss recent evidence that Ihh may be one of the key epithelial signals that indicates epithelial integrity to the underlying mesenchyme.
Nikè V J A Büller; Sanne L Rosekrans; Jessica Westerlund; Gijs R van den Brink
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiology (Bethesda, Md.)     Volume:  27     ISSN:  1548-9221     ISO Abbreviation:  Physiology (Bethesda)     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101208185     Medline TA:  Physiology (Bethesda)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  148-55     Citation Subset:  IM    
Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology & Hepatology, Academic Medical Center, Amsterdam, The Netherlands.
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