Document Detail


Hedgehog signaling and maintenance of homeostasis in the intestinal epithelium.
MedLine Citation:
PMID:  22689790     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Homeostasis of the rapidly renewing intestinal epithelium depends on a balance between cell proliferation and loss. Indian hedgehog (Ihh) acts as a negative feedback signal in this dynamic equilibrium. We discuss recent evidence that Ihh may be one of the key epithelial signals that indicates epithelial integrity to the underlying mesenchyme.
Authors:
Nikè V J A Büller; Sanne L Rosekrans; Jessica Westerlund; Gijs R van den Brink
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiology (Bethesda, Md.)     Volume:  27     ISSN:  1548-9221     ISO Abbreviation:  Physiology (Bethesda)     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101208185     Medline TA:  Physiology (Bethesda)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  148-55     Citation Subset:  IM    
Affiliation:
Tytgat Institute for Liver and Intestinal Research, Department of Gastroenterology & Hepatology, Academic Medical Center, Amsterdam, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Interventional and intrinsic airway homeostasis and repair.
Next Document:  Orphan nuclear receptors and the regulation of nutrient metabolism: understanding obesity.