| Heavy ion radiotherapy during pregnancy. | |
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MedLine Citation:
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PMID: 20493478 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To provide a safe particle therapy treatment for a pregnant woman with skull-base cancer. DESIGN: Case report. SETTING: University clinic. PATIENT(S): A 27-year-old woman diagnosed for a skull-base chordoma and whose pregnancy was found during the course of radiotherapy with accelerated carbon ions. INTERVENTION(S): Therapy was continued as scheduled, and fetal dose produced by photons and neutrons was measured at each radiotherapy fraction using passive and active monitors. MAIN OUTCOME MEASURE(S): Radiation dose to the uterus. Health of the mother and the newborn. RESULT(S): Total dose to the uterus was <0.2 mSv. About 30% of this dose was caused by neutrons. Magnetic resonance imaging of the skull base showed no evidence of recurrent disease in the mother. The child was healthy with normal development. CONCLUSION(S): Heavy ion cancer therapy produces a very low dose in distal organs. |
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Authors:
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Marc W Münter; Marc Wengenroth; Georg Fehrenbacher; Dieter Schardt; Anna Nikoghosyan; Marco Durante; Jürgen Debus |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-05-20 |
Journal Detail:
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Title: Fertility and sterility Volume: 94 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-27 Completed Date: 2010-12-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 2329.e5-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Radiation Oncology, University of Heidelberg, Heidelberg, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Carbon Radioisotopes / therapeutic use Chordoma / radiotherapy* Female Heavy Ions / therapeutic use* Humans Infant, Newborn Male Pregnancy Pregnancy Complications, Neoplastic / radiotherapy* Radiation Protection Radiometry Skull Base Neoplasms / radiotherapy* |
| Chemical | |
Reg. No./Substance:
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0/Carbon Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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