| Heavy Metals Exposure and Hearing Loss in US Adolescents. | |
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MedLine Citation:
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PMID: 22183895 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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METHODS: We evaluated the cross-sectional associations between blood lead, blood mercury, and urinary cadmium and arsenic levels and audiometrically determined hearing loss in participants aged 12 to 19 years in the 2005-2008 National Health and Nutrition Examination Survey after accounting for the complex survey design. There were 2535 individuals available for analysis of blood lead and mercury levels, 878 for urinary cadmium levels, and 875 for urinary arsenic levels. Multivariate logistic regression was used to calculate adjusted odds ratios (ORs) and 95% CIs. RESULTS: A blood lead level greater than or equal to 2 μg/dL (to convert to micromoles per liter, multiply by 0.0483) compared with less than 1 μg/dL was associated with increased odds of high-frequency hearing loss (OR, 2.22; 95% CI, 1.39-3.56). Individuals in the highest quartile of urinary cadmium levels had significantly higher odds of low-frequency hearing loss than those in the lowest quartile (OR, 3.08; 95% CI, 1.02-9.25). There was no overall association between quartiles of blood mercury or urinary arsenic levels and hearing loss. CONCLUSION: Blood lead levels well below the current recommended action level are associated with substantially increased odds of high-frequency hearing loss. |
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Authors:
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Josef Shargorodsky; Sharon G Curhan; Elisabeth Henderson; Roland Eavey; Gary C Curhan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of otolaryngology--head & neck surgery Volume: 137 ISSN: 1538-361X ISO Abbreviation: Arch. Otolaryngol. Head Neck Surg. Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8603209 Medline TA: Arch Otolaryngol Head Neck Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1183-9 Citation Subset: AIM; IM |
Affiliation:
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Channing Laboratory, 181 Longwood Ave, Boston, MA 02115. Josef_Shargorodsky@meei.harvard.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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