| Heat-stable alkaline phosphatase. A putative tumor marker of head and neck squamous cell carcinoma. | |
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MedLine Citation:
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PMID: 7865236 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Serum total alkaline phosphatase (AP) activity and heat-stable AP (HSAP) were investigated in patients with uncontrolled squamous cell carcinoma of the head and neck before and after treatment. No significant differences in AP activity were seen between normal subjects and cancer patients. However, the HSAP fraction of the total AP activity was significantly elevated prior to treatment and the level declined and remained low during successful treatment, while it increased with tumor progression or recurrences. Heat-stable AP was found to be a useful tumor marker of potential usefulness in the management of patients with squamous cell carcinoma of the head and neck. |
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Authors:
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M B Rassam; N N al-Bashir; A R al-Salihi; M H Hammash; F T al-Sammerai; M A al-Ubaidi; I N Waheed |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta oncologica (Stockholm, Sweden) Volume: 34 ISSN: 0284-186X ISO Abbreviation: Acta Oncol Publication Date: 1995 |
Date Detail:
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Created Date: 1995-03-28 Completed Date: 1995-03-28 Revised Date: 2009-05-12 |
Medline Journal Info:
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Nlm Unique ID: 8709065 Medline TA: Acta Oncol Country: NORWAY |
Other Details:
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Languages: eng Pagination: 49-52 Citation Subset: IM |
Affiliation:
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Department of Chemistry and Biochemistry, Saddam College of Medicine, Baghdad, Iraq. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Alkaline Phosphatase / blood* Analysis of Variance Carcinoma, Squamous Cell / enzymology* Disease Progression Female Head and Neck Neoplasms / enzymology* Hot Temperature Humans Male Middle Aged Recurrence Tumor Markers, Biological / blood* |
| Chemical | |
Reg. No./Substance:
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0/Tumor Markers, Biological; EC 3.1.3.1/Alkaline Phosphatase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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