Document Detail


Heat shock proteins and the pancreas.
MedLine Citation:
PMID:  12704647     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Heat shock proteins (HSPs) are cytoprotective molecules that help to maintain the metabolic and structural integrity of cells. In this review, we briefly discuss the regulation and function of HSPs. The review focuses on the current knowledge of pancreatic HSP induction, the HSP level changes during acute pancreatitis, the potential effects of the pre- and co-induction of HSPs in experimental acute pancreatitis, and the mechanisms by which HSPs might mediate cellular protection.
Authors:
Zoltán Rakonczay; Tamás Takács; Imre Boros; János Lonovics
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Journal of cellular physiology     Volume:  195     ISSN:  0021-9541     ISO Abbreviation:  J. Cell. Physiol.     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-04-21     Completed Date:  2003-05-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0050222     Medline TA:  J Cell Physiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  383-91     Citation Subset:  IM    
Copyright Information:
Copyright 2003 Wiley-Liss, Inc.
Affiliation:
First Department of Medicine, University of Szeged, Hungary. raz@in1st.szote.u-szeged.hu
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Animals
Carcinoma / genetics,  metabolism
Chronic Disease
Cytoprotection
Heat-Shock Proteins / biosynthesis*,  genetics,  physiology*
Heat-Shock Response
Humans
Pancreas / metabolism*
Pancreatic Neoplasms / genetics,  metabolism
Pancreatitis / metabolism
RNA, Messenger / biosynthesis
Chemical
Reg. No./Substance:
0/Heat-Shock Proteins; 0/RNA, Messenger

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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