| HeartMate left ventricular assist devices: a multigeneration of implanted blood pumps. | |
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MedLine Citation:
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PMID: 11403676 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The HeartMate family of implanted left ventricular assist devices (LVADs) developed by Thermo Cardiosystems, Inc. (TCI) span a time frame that goes back to the beginning of clinical use of mechanical circulatory support and will stretch well into the foreseeable future. Associated blood pump technology employed in the HeartMates range from an original pusher plate concept to the most advanced rotary pump devices. Starting initially with a pneumatic actuated pusher plate pump, clinical use of the HeartMate I began in 1986. In 1990, electric motor-actuated versions of the HeartMate I began to be used clinically. Presently, the HeartMate I has been implanted in some 2,300 patients worldwide, and this LVAD is a standard by which all others are currently measured. Following the HeartMate I is TCI's next-generation, the HeartMate II, a rotary-pump-based LVAD that uses an axial flow blood pump having blood immersed mechanical bearings. Clinical trials of the HeartMate II were initiated in 2000. The HeartMate III, representing TCI's next-generation LVAD, is structured around a centrifugal blood pump that uses a magnetically levitated rotating assembly. Compared to the HeartMate II, the HeartMate III has the potential for higher overall efficiency. The pump's operating life is not dependent on bearing wear. Given the significantly advanced LVAD technology represented by HeartMates II and III, coupled with the experience of HeartMate I, TCI is well-poised to keep its LVAD products as industry standards in the future. |
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Authors:
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T R Maher; K C Butler; V L Poirier; D B Gernes |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Artificial organs Volume: 25 ISSN: 0160-564X ISO Abbreviation: Artif Organs Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-06-13 Completed Date: 2001-07-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7802778 Medline TA: Artif Organs Country: United States |
Other Details:
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Languages: eng Pagination: 422-6 Citation Subset: IM |
Affiliation:
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Nimbus Inc., Rancho Cordova, California, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Heart-Assist Devices* Humans Male Middle Aged Prosthesis Design* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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