Document Detail

Heart valve operations in patients with active infective endocarditis.
MedLine Citation:
PMID:  2339925     Owner:  NLM     Status:  MEDLINE    
Sixty-two consecutive patients underwent heart valve operation for active infective endocarditis. There were 42 men and 20 women whose mean age was 49 years (range, 21 to 79 years). The infection was in the aortic valve in 37 patients, the mitral valve in 18, the aortic and mitral valves in 5, and the tricuspid valve in 2. Twenty-four patients had prosthetic valve endocarditis. Staphylococcus and Streptococcus were responsible for 86% of the infections. Annular abscess was encountered in 33 patients. Complex valve procedures involving reconstruction of the left ventricular inflow or outflow tract or both were performed in 31 patients. There were three operative deaths (4.8%). Predictors of operative mortality were prosthetic valve endocarditis, preoperative shock, and annular abscess. Patients were followed for 1 month to 130 months (mean follow-up, 43 months). Only 1 patient required reoperation for persistent infection. There were ten late deaths. Most survivors (96%) are currently in New York Heart Association class I or II. The 5-year actuarial survival was 79% +/- 7%. These data demonstrate excellent results in patients with native valve endocarditis, and support the premise that patients with prosthetic valve endocarditis should have early surgical intervention.
T E David; J Bos; G T Christakis; P R Brofman; D Wong; C M Feindel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  49     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-06-19     Completed Date:  1990-06-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  701-5; discussion 712-3     Citation Subset:  AIM; IM    
Division of Cardiovascular Surgery, Toronto Western Hospital, Ontario, Canada.
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MeSH Terms
Endocarditis, Bacterial / mortality,  surgery*
Follow-Up Studies
Intraoperative Period / mortality
Middle Aged
Postoperative Complications / therapy
Staphylococcal Infections / mortality,  surgery
Streptococcal Infections / mortality,  surgery
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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