Document Detail

Heart transplant for anomalous origin of left coronary artery from pulmonary artery.
MedLine Citation:
PMID:  12537235     Owner:  NLM     Status:  MEDLINE    
Anomalous origin of the left coronary artery from the pulmonary artery is a congenital coronary artery malformation most commonly present in infancy. A variety of surgical procedures have been described to achieve physiological correction of the coronary flow abnormalities. These techniques are effective as long as there is potential for myocardial recovery. However the sequelae of chronic myocardial ischemia that characterize this entity often irreversibly damage the heart and preclude correction and palliation of the native anomaly. In this type of setting, heart transplantation is a realistic option. Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) occasionally presents in adulthood. Anatomic repair with a two coronary artery system may not be optimal in patients presenting with ischemic cardiomyopathy. We report an adult patient with platelet factor 4 (PF4) antibodies who underwent orthotopic heart transplantation (OHT) for ALCAPA.
Kiron K S Nair; Lawrence S Zisman; Ellis Lader; Aneta Dimova; Charles C Canver
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  75     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2003-01-22     Completed Date:  2003-02-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  282-4; discussion 284-5     Citation Subset:  AIM; IM    
Heart Institute, Albany Medical College, Albany, NY 12208-3479, USA.
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MeSH Terms
Autoantibodies / analysis
Coronary Vessel Anomalies / surgery*
Heart Transplantation*
Middle Aged
Platelet Factor 4 / immunology
Pulmonary Artery / abnormalities*
Reg. No./Substance:
0/Autoantibodies; 37270-94-3/Platelet Factor 4

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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