Document Detail


Heart rupture predictors in Spanish myocardial infarction patients: evaluation using propensity score analysis.
MedLine Citation:
PMID:  20424560     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The aim was to evaluate factors associated with the development of heart rupture in a Spanish registry of acute myocardial infarction (AMI) patients.
MATERIAL/METHODS: This was a retrospective study of cohorts, including all patients diagnosed with AMI included in the ARIAM Spanish multicenter registry. The study period was from June 1996 to December 2005. The follow-up period was limited to the time of stay in intensive care or coronary care units. Multivariate logistic regression was used to study the factors associated with the development of heart rupture. A propensity score analysis was also performed to determine the involvement of beta blockers, ACE inhibitors, and fibrinolytics in the development of heart rupture.
RESULTS: 16,815 AMI patients were included. Heart rupture occurred in 477 (2.8%). Heart rupture was associated with female gender, older age, the absence of previous infarct, and the administration of thrombolysis, while ACE inhibitors and beta blockers acted as protective variables. The propensity score analysis showed that fibrinolysis was a variable associated with heart rupture except in the younger subgroup and in the subgroup with less delay in administration. It was also found that beta blockers and ACE inhibitors are variables providing protection against heart rupture.
CONCLUSIONS: Heart rupture is associated with older age, female gender, absence of previous infarct, and the administration of thrombolysis, while ACE inhibitors and beta blockers seem to prevent this complication.
Authors:
Manuel Ruiz-Bailén; Manuela Expósito-Ruiz; Ana-María Castillo-Rivera; Luis Rucabado-Aguilar; María Isabel Ruiz-García; José-Angel Ramos-Cuadra; Andrés Ruiz-Valverde; Javier Gómez-Jiménez; José-Luis Benitez-Parejo; José Cuñat de la Hoz; Francisco Felices Abat; Jesús Pérez Valenzuela;
Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Medical science monitor : international medical journal of experimental and clinical research     Volume:  16     ISSN:  1643-3750     ISO Abbreviation:  Med. Sci. Monit.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-28     Completed Date:  2010-08-05     Revised Date:  2011-06-14    
Medline Journal Info:
Nlm Unique ID:  9609063     Medline TA:  Med Sci Monit     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  PH49-56     Citation Subset:  IM    
Affiliation:
Intensive Care Unit, Critical Care and Emergency Department, Hospital Universitario Médico-Quirúrgico del Complejo Hospitalario de Jaén, Jaén University, Spain. mrb1604@terra.es
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MeSH Terms
Descriptor/Qualifier:
Aged
Female
Heart Rupture / epidemiology*
Humans
Incidence
Male
Middle Aged
Retrospective Studies
Risk Factors
Spain / epidemiology
Investigator
Investigator/Affiliation:
Manuel Ruiz Bailén / ; J A Ramos Cuadra / ; J L Fierro Rosón / ; A Cárdenas Cruz / ; J F Martínez Coronel / ; F Barrero Acedo / ; S Martínez Escobar / ; F J Rodríguez Pérez / ; F J Delgado Vilchez / ; J Córdoba Escames / ; A Sánchez Rodríguez / ; P Cobos Castellanos / ; J Rodríguez Medina / ; J C Rodríguez Yáñez / ; J Gil Cebrián / ; José Arias Garrido / ; Antonio Rodríguez Zapallo / ; L Vallejo Sánchez / ; C de la Fuente Martos / ; R Toro Sánchez / ; F Dios Torronteras / ; A Guerrero Arjona / ; E Lopera Lopera / ; F Contreras Molina / ; J M Molina Cantero / ; J L Bellot Iglesias / ; M I Rodríguez Higueras / ; P Ramos / ; S Ruiz Navarro / ; A Reina Toral / ; E Aguayo de Hoyos / ; M Colmenero Ruiz / ; M M Jiménez Quintana / ; F Barranco Ruiz / ; S Shiaffino Cano / ; J M Torres Ruiz / ; J M Mercado Ramos / ; I Macias Guarasa / ; M A Fernández Sacristán / ; E del Campo Molina / ; L I Rucabado Aguilar / ; J L Muñoz Muñoz / ; E Castillo Lorente / ; A Carrillo Garrido / ; A de Molina Ortega / ; J A Camacho Pulido / ; A Montijano Vizcaíno / ; A Bartolomé Sanz / ; M M Sánchez Zorrilla Sanz / ; J A Ferriz Martín / ; T García Paredes / ; J C Escudero Valera / ; A García Alcántara / ; María Victoria de la Torre Prados / ; Javier Merino Vega / ; A Varela López / ; G Quesada García / ; M Zaheri Beryanaki / ; A Vázquez Vicente / ; J I Mateo Sánchez / ; J M García Alvarez / ; A Poullet Brea / ; A García García / ; F Castillo Guerrero / ; J A Arboleda / ; R Siendones / ; J Prieto de Paula / ; Y Fernández Jurado / ; B Maza / ; R Enamorado / ; J Maraví Petri / ; A García Lombardo / ; J Fajardo López-Cuervo / ; F Ríos Ortíz / ; E Civeira / ; I Gutiérrez Cia / ; J González Cortijo / ; G Olivar Duplá / ; J M Vega / ; J A Lapuerta / ; M González / ; J Megido / ; R Fernández-Cid Bouza / ; M A González López / ; C de la Rubia de Gracia / ; F Cabeza Cabeza / ; P Ventura Ventura / ; L Fajardo Feo / ; P Cancelo Suarez / ; A Montón Rodríguez / ; M Arroyo García / ; A Zabalegui Pérez / ; J Armentia Fructuoso / ; Z Ferreras Paez / ; C Ruiz Pardo / ; F Cañizares Castellanos / ; C H Martínez Jiménez / ; B Alvarez Martínez / ; J J Sandoval Garzón / ; J B López Messa / ; C Berrocal de la Fuente / ; J J Cortina Gómez / ; P Ancillo García / ; M A Taberna Izquierdo / ; P Medina Santaolalla / ; J J Sanz Hernán / ; P Velasco / ; S Armengol / ; A López / ; L Oussedick / ; J Berrade / ; A Rovira / ; E Bosch / ; J M Alcoberro / ; P Laguardia / ; M Piqué / ; B Balsera / ; R Alcega / ; S Alonso / ; J Mariné / ; J Rello / ; R Claramonte / ; I Forcadell / ; G Masdeu / ; Y del Castillo / ; P Espinosa / ; P Jubert / ; M Nolla / ; R Diaz Boladeras / ; M Valdés / ; J Nava / ; J Costa / ; A Ochagavia / ; F Baigorri / ; C Sala / ; P Velasco / ; A Rovira / ; J M Alcoberro / ; X Balanzó / ; I Vallverdú / ; B Balsera / ; S Alonso / ; J Rello / ; R Claramonte Porcar / ; I Forcadell Ferré / ; G Masdeu Eixarch / ; F Bodí / ; M L Centeno / ; S Calvo Barros / ; P Jiménez Gómez / ; J M Gulias López / ; J González Tutor / ; C J Fernández González / ; A M Ferreiro González / ; M L Martínez Rodríguez / ; A Díaz Lamas / ; R Rodríguez Alvarez-Granados / ; E Rodríguez García / ; M J de la Torre Fernández / ; C Miguez Baños / ; A País Almozara / ; D Vila Fernández / ; J Fandiño Pena / ; S López Astral / ; A Canabal / ; L Navarro / ; J C Pérez / ; E de la Fuente / ; S Temprano Vázquez / ; F del Nogal Sáez / ; J Rebollo Ternero / ; J López Martín / ; T Grau / ; J J Oñoro Cañavera / ; V Gómez Tello / ; J L Moreno Hurtrez / ; J D García / ; J L Soria / ; A García de la Gandara / ; S Plaza García / ; V Barrio Nebreda / ; P López Lorente / ; E Cereijo / ; J Miquel / ; F J Goizueta / ; M Quintana / ; A Simón Martín / ; J González Rodríguez / ; S García Plaza / ; V Barrio Nebreda / ; M Rodríguez / ; Francisco Ríos / ; F Felices Abad / ; C Palazón Sánchez / ; S Nicolás Franco / ; J Rodríguez / ; A Sánchez / ; A Carrillo Alcaraz / ; P Jara / ; A Manrique / ; F Sos / ; G Hernando / ; F J Ochoa / ; J Cánovas Robles / ; C García-Romeu García / ; M Díaz Barranco / ; C Ruiperez Cebrian / ; M Pérez Avilés / ; F Ballenilla Antón / ; R Nogueira Collado / ; F Guardiola Navarro / ; A Roche / ; F Criado Rodríguez / ; J M Carrasco Barea /

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