Document Detail


Heart rhythm at the time of death documented by an implantable loop recorder.
MedLine Citation:
PMID:  20019013     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: The aims of this study were to describe arrhythmias documented with an implantable loop recorder (ILR) in post-acute myocardial infarction (AMI) patients with left ventricular dysfunction at the time of death and to establish the correlation to mode of death. METHODS AND RESULTS: Post-mortem ILR device interrogations were analysed from patients dying in the CARISMA study. Mode of death was classified by a modified CAST classification. Twenty-six patients died with an implanted ILR. Of these, 16 had an electrocardiogram recorded at the time of death. Ventricular tachycardia (VT)/ventricular fibrillation (VF) was terminal rhythm in eight patients and bradyarrhythmias were observed in another eight patients. Of the deaths with peri-mortem recordings, seven were classified as sudden cardiac death (SCD). In six of these, VF was documented at the time of death. Six monitored deaths were classified as non-SCD (NSCD) of which only two had recordings of VT/VF, whereas four had bradyarrhythmias. All peri-mortem recordings in non-cardiac death (NCD) were bradyarrhythmia. CONCLUSION: Long-term monitoring in a population of post-AMI patients with left ventricular ejection fraction < or =40% showed that VT/VF and bradyarrhythmia each accounted for half of the recorded events at the time of death. The ILR confirmed that ventricular tachyarrhythmias are associated primarily with SCD, whereas bradyarrhythmias and electromechanical dissociation seems dominant in NSCD and NCD. The study was registered at ClinicalTrials.gov: NCT00145119.
Authors:
Uffe Jakob Ortved Gang; Christian J?ns; Rikke M?rch J?rgensen; Steen Zabell Abildstr?m; Jens Haarbo; Marc D Messier; Heikki V Huikuri; Poul Erik Bloch Thomsen;
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Publication Detail:
Type:  Clinical Trial; Journal Article     Date:  2009-12-16
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  12     ISSN:  1532-2092     ISO Abbreviation:  Europace     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-21     Completed Date:  2010-06-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  254-60     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Copenhagen University Hospital Gentofte, Niels Andersens Vej 65, Internal Post 4210, 2900 Hellerup, Denmark. dr.gang@dadlnet.dk
Data Bank Information
Bank Name/Acc. No.:
ClinicalTrials.gov/NCT00145119
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Bradycardia / diagnosis,  epidemiology,  physiopathology*
Cause of Death*
Electrocardiography
Electrocardiography, Ambulatory / instrumentation*,  methods
Female
Follow-Up Studies
Heart Rate / physiology*
Humans
Incidence
Male
Middle Aged
Myocardial Infarction / complications
Retrospective Studies
Risk Factors
Stroke Volume / physiology
Tachycardia, Ventricular / diagnosis,  epidemiology,  physiopathology*
Ventricular Fibrillation / diagnosis,  epidemiology,  physiopathology*
Investigator
Investigator/Affiliation:
M P Raatikainen / ; J Hartikainen / ; V Virtanen / ; J Boland / ; O Anttonen / ; N Hoest / ; L V A Boersma / ; E S Platou / ; D Becker / ; G Schrijver / ; H Robbe / ; V Mahaux / ; L K Christiansen /

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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