Document Detail


Heart-rate variability in chronic traumatic brain injury.
MedLine Citation:
PMID:  9171929     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Heart-rate variability (HRV), a measure of fluctuation around the mean heart rate, reflects the sympathetic and parasympathetic balance of the autonomic nervous system, and is an excellent technique to study cardiovascular tone in patients with neurological injuries. The purpose of this study was to determine whether abnormal HRV is present in patients with traumatic brain injury (TBI) during the post-acute recovery phase. Using a prospective, case/control design, we performed 24-h ambulatory ECG monitoring in seven TBI patients and in seven controls (C). There was a significant difference in root mean squared successive difference of RR intervals (C 40.4 +/- 10.3, TBI 23.3 +/- 16.5, p = 0.04) between TBI and C. Four patients with TBI (compared to one control) had abnormal standard deviation of the RR interval. When these four patients were compared to their matched controls, significant differences were found in frequency domain measure (In total power: TBI 4.4 +/- 0.9 ms2, C 7.1 +/- 1.4 ms2, In low frequency: TBI 3.3 +/- 1.1 ms2, C 6.4 +/- 1.4 ms2; In high frequency TBI 2.0 +/- 1.0 ms2, C 4.8 +/- 1.3 ms2, all p < 0.05). Thus, abnormalities in both time and frequency domains of HRV are present in TBI during the post-acute recovery phase.
Authors:
M L King; S W Lichtman; G Seliger; F A Ehert; J S Steinberg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Brain injury : [BI]     Volume:  11     ISSN:  0269-9052     ISO Abbreviation:  Brain Inj     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-07-22     Completed Date:  1997-07-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8710358     Medline TA:  Brain Inj     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  445-53     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Helen Hayes Hospitall, West Haverstraw, New York 10993, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Brain Injuries / physiopathology*
Case-Control Studies
Chronic Disease
Electrocardiography, Ambulatory
Female
Heart Rate*
Humans
Male
Prospective Studies
Reference Values

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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