Document Detail

Heart-rate variability in brain-damaged adults.
MedLine Citation:
PMID:  66430     Owner:  NLM     Status:  MEDLINE    
To test whether or not the characteristics of the adult heart-rate reflect the condition of the central nervous system (as they seem to do in the fetus), ten patients with neurological deficits of acute onset were studied. No patients had received drugs and none was hypoxic. The findings indicate that the normal cyclic changes in heart-rate are reduced in the presence of severe brain damage. Variability decreases rapidly if intracranial pressure rises, and the rate of return of variability reflects the subsequent state of neuronal function, even when intracranial pressure has been restored to normal. In this limited setting, then, it appears that heart-rate variability may reflect the functional state of the central nervous system.
R I Lowensohn; M Weiss; E H Hon
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Lancet     Volume:  1     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1977 Mar 
Date Detail:
Created Date:  1977-05-12     Completed Date:  1977-05-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  626-8     Citation Subset:  AIM; IM    
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MeSH Terms
Aneurysm / complications
Basilar Artery
Brain Concussion / physiopathology*
Heart Catheterization
Heart Rate*
Intracranial Pressure
Subarachnoid Hemorrhage / etiology,  physiopathology*

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