Document Detail

Heart rate variability as a marker of myocardial perfusion.
MedLine Citation:
PMID:  10085482     Owner:  NLM     Status:  MEDLINE    
RR variability (HRV), an independent predictor of death following myocardial infarction, may also be related to other features of coronary artery disease. We evaluated its ability to differentiate among sedentary patients with chest pain >/=45 years of age demonstrating either normal or abnormal myocardial perfusion with rest and exercise thallium-210 tomographic imaging. The major HRV difference between 48 men and 50 women with normal perfusion was a significantly higher high frequency power in women. No significant differences in mean HRV values were found between the 57 men with abnormal perfusion scans and the 48 men with normal perfusion. In both men and women with normal perfusion scans, duration of exercise was significantly related to age. In men with abnormal scans, impaired myocardial perfusion alters the relationship between exercise duration and age, and a group of individuals with diminished HRV and low levels of physical fitness, regardless of age, can be identified. Despite these latter selective findings, we conclude that HRV is not a sensitive indicator to differentiate patients with normal and abnormal myocardial perfusion.
D Schechter; D Sapoznikov; M H Luria; S Mendelson; M Bocher; R Chisin
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology     Volume:  90     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1998  
Date Detail:
Created Date:  1999-06-03     Completed Date:  1999-06-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  239-43     Citation Subset:  IM    
Department of Medical Biophysics and Nuclear Medicine, Hadassah University Hospital, Jerusalem, Israel.
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MeSH Terms
Age Factors
Chest Pain / physiopathology
Coronary Circulation / physiology*
Coronary Vessels / physiology*,  radionuclide imaging
Exercise Test
Heart Rate / physiology*
Life Style
Middle Aged
Sex Factors
Thallium Radioisotopes
Time Factors
Tomography, Emission-Computed
Reg. No./Substance:
0/Thallium Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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