Document Detail

Heart rate response profiles during head upright tilt test in infants with apparent life threatening events.
MedLine Citation:
PMID:  9059156     Owner:  NLM     Status:  MEDLINE    
Sympatheticovagal imbalance causing episodes of severe bradycardia has been suggested as a cause of apparent life threatening events (ALTEs). The autonomic control of the heart rate in 18 infants with ALTEs and 12 controls was evaluated by the head upright tilt test. Five different heart rate response profiles (compared with the baseline) were observed during the tilt: (1) increase followed by a decrease and return to baseline; (2) sustained increase; (3) decrease followed by an increase and return to baseline; (4) sustained decrease; (5) no change. Eighty eight per cent of controls responded with heart rate increase followed by decrease or sustained increase compared with 55% of infants with an ALTE; a significantly greater proportion of infants with ALTEs than controls responded with heart rate decrease or no change in rate (45% v 8%). This altered reaction during a head upright tilt test may be an expression of an underlying autonomic dysfunction in infants who have experienced an ALTE.
A Edner; M Katz-Salamon; H Lagercrantz; J Milerad
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  76     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1997 Jan 
Date Detail:
Created Date:  1997-03-21     Completed Date:  1997-03-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  27-30     Citation Subset:  AIM; IM    
Department of Paediatrics, Karolinska Hospital, Stockholm, Sweden.
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MeSH Terms
Case-Control Studies
Heart Rate / physiology*
Sleep Apnea Syndromes / physiopathology*
Tilt-Table Test

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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