Document Detail

Heart rate recovery is lower following supine exercise in asymptomatic hereditary hemochromatosis subjects compared with healthy controls.
MedLine Citation:
PMID:  17558198     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Heart rate recovery (HRR) has become an important diagnostic and prognostic marker in recent years. Subjects with hereditary hemochromatosis (HH) demonstrate arterial wall changes that reduce compliance. Arterial compliance may influence HRR by altering baroreceptor discharge. The purpose of the present study is to examine differences in HRR between subjects with HH and healthy controls during treadmill (TM) and supine lower extremity ergometry (SLEE) exercise testing. METHODS: Forty subjects with asymptomatic HH (27 men/13 women; mean age: 49.7 +/- 9.9 years) and 21 healthy controls (14 men/7 women; mean age: 47.8 +/- 8.4 years) participated in this study. Each subject underwent a symptom-limited 25-W Supine Lower Extremity Ergometry (SLEE) and Bruce TM exercise test within 1 week of each other. Heart rate recovery was the value obtained at 1 minute postexercise. Peak heart rate, systolic blood pressure, and the double product were also obtained during each exercise test. RESULTS: Peak heart rate was significantly higher, whereas HRR and peak systolic blood pressure were significantly lower during TM compared with SLEE exercise testing in both groups (P < .01). A significantly lower HRR during SLEE in subjects with HH was the only significant difference between groups (35.4 +/- 9.0 vs. 29.2 +/- 8.5, P < .01). DISCUSSION: Heart rate recovery was not significantly different between HH and control subjects during upright exercise. However, HRR was significantly lower during SLEE in HH subjects compared with controls. A higher venous return during SLEE may have allowed for differences in arterial compliance between groups to influence HRR.
Ross Arena; Yukitaka Shizukuda; Charles D Bolan; Dorothy J Tripodi; Yu-Ying Yau; Kevin P Smith; Myron A Waclawiw; Susan F Leitman; Douglas R Rosing
Related Documents :
761318 - Ontogenetic increase of the maximal rate of rise of the chick embryonic heart action po...
12682838 - Post-exercise vitamin c supplementation and recovery from demanding exercise.
24274868 - Role of exercise in optimizing the functional status of patients with nonalcoholic fatt...
2450938 - Comparison of different volume markers in peritoneal dialysis.
2404708 - Chronic obstructive pulmonary disease. current concepts and therapeutic approaches.
1753728 - Effects of flexibility training on enhancing spinal mobility in older women.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cardiopulmonary rehabilitation and prevention     Volume:  27     ISSN:  1932-7501     ISO Abbreviation:  -     Publication Date:    2007 May-Jun
Date Detail:
Created Date:  2007-06-11     Completed Date:  2007-07-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101291247     Medline TA:  J Cardiopulm Rehabil Prev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  157-60     Citation Subset:  IM    
Department of Physical Therapy, Virginia Commonwealth University, VA 23298-0224, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Blood Pressure / physiology
Case-Control Studies
Exercise Test*
Heart Rate / physiology*
Hemochromatosis / genetics,  physiopathology*
Iron / blood
Middle Aged
Recovery of Function / physiology*
Supine Position / physiology
Systole / physiology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Paraoxonase activity following exercise-based cardiac rehabilitation program.
Next Document:  Indicators of functional deficits after coronary artery bypass surgery.